Protein Alignment NCK1 and Nck1

DIOPT Version :9

• Sequence 1: NP_001278928.1
• Gene: NCK1 / 4690
• HGNCID: 7664
• Length: 377
• Species: Homo sapiens
• Sequence 2: NP_035008.2
• Gene: Nck1 / 17973
• MGIID: 109601
• Length: 377
• Species: Mus musculus
• Alignment Length: 377
• Identity: 373/377 - (98%)
• Similarity: 377/377 - (100%)
• Gaps: 0/377 - (0%)

Human     1 MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKA 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MAEEVVVVAKFDYVAQQEQELDIKKNERLWLLDDSKSWWRVRNSMNKTGFVPSNYVERKNSARKA 65

Human    66 SIVKNLKDTLGIGKVKRKPSVPDSASPADDSFVDPGERLYDLNMPAYVKFNYMAEREDELSLIKG 130
            |||||||||||||||||||||||:||||||||||||||||||||||:||||||||||||||||||
Mouse    66 SIVKNLKDTLGIGKVKRKPSVPDTASPADDSFVDPGERLYDLNMPAFVKFNYMAEREDELSLIKG 130

Human   131 TKVIVMEKCSDGWWRGSYNGQVGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVLHVV 195
            |||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||
Mouse   131 TKVIVMEKCSDGWWRGSYNGQIGWFPSNYVTEEGDSPLGDHVGSLSEKLAAVVNNLNTGQVLHVV 195

Human   196 QALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTVMQNNPLTSGLE 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||
Mouse   196 QALYPFSSSNDEELNFEKGDVMDVIEKPENDPEWWKCRKINGMVGLVPKNYVTIMQNNPLTSGLE 260

Human   261 PSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQG 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 PSPPQCDYIRPSLTGKFAGNPWYYGKVTRHQAEMALNERGHEGDFLIRDSESSPNDFSVSLKAQG 325

Human   326 KNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS 377
            ||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 KNKHFKVQLKETVYCIGQRKFSTMEELVEHYKKAPIFTSEQGEKLYLVKHLS 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NCK1	NP_001278928.1	SH3_Nck1_1	3..61	CDD:212833	57/57 (100%)
		SH3_Nck1_2	108..162	CDD:212834	51/53 (96%)
		SH3_Nck1_3	193..249	CDD:212837	55/55 (100%)
		SH2_Nck1	280..376	CDD:198271	95/95 (100%)
Nck1	NP_035008.2	SH3_Nck1_1	3..61	CDD:212833	57/57 (100%)
		SH3_Nck1_2	108..162	CDD:212834	51/53 (96%)
		SH3_Nck1_3	193..249	CDD:212837	55/55 (100%)
		SH2_Nck1	280..376	CDD:198271	95/95 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83964047
Domainoid	1	1.000	159	1.000	Domainoid score	I32277
eggNOG	1	0.900	-	-		E1_KOG4226
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38148
Inparanoid	1	1.050	774	1.000	Inparanoid score	I8252
Isobase	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG46567
OrthoDB	1	1.010	-	-		D1097449at2759
OrthoFinder	1	1.000	-	-		FOG0002240
OrthoInspector	1	1.000	-	-		oto116348
orthoMCL	1	0.900	-	-		OOG6_106243
Panther	1	1.100	-	-	LDO	PTHR19969
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4150
SonicParanoid	1	1.000	-	-		X1672
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	18	18.300