DRSC/TRiP Functional Genomics Resources

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Protein Alignment NCAM1 and DIP-gamma

DIOPT Version :9

Sequence 1:NP_001229536.1 Gene:NCAM1 / 4684 HGNCID:7656 Length:884 Species:Homo sapiens
Sequence 2:NP_651649.1 Gene:DIP-gamma / 43417 FlyBaseID:FBgn0039617 Length:413 Species:Drosophila melanogaster


Alignment Length:350 Identity:82/350 - (23%)
Similarity:134/350 - (38%) Gaps:93/350 - (26%)


- Green bases have known domain annotations that are detailed below.


Human   220 IVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQI----------------EQEEDDEKYIFSDD 268
            |.|.|...|:...|.|......:..:.|.:..:|.                ...:|...:     
  Fly    45 INNVTYPAGREAILACSVRNLGKNKVGWLRASDQTVLALQGRVVTHNARISVMHQDMHTW----- 104

Human   269 SSQLTIKKVDKNDEAEYIC-IAENKAGEQDATIHLKVFAKPKITYVENQT--AMELEEQVTLTCE 330
              :|.|.|:.::|...|:| |..:...:|...|.::|  .|.|...|:..  |::..|..||||:
  Fly   105 --KLKISKLRESDRGCYMCQINTSPMKKQVGCIDVQV--PPDIINEESSADLAVQEGEDATLTCK 165

Human   331 ASGDPIPSITWRTSTRNISSEEKASWTRPEKQEVHAPWNWQVGRQKGQAGSAGFPGSHETLDGHM 395
            |:|:|.|.:|||                               |:.|:......|||.|.    |
  Fly   166 ATGNPQPRVTWR-------------------------------REDGEMILIRKPGSREL----M 195

Human   396 VVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQD-SQSMYLEVQYAPKLQGPVAVY-TWEGNQV 458
            .|.|: ..|||.|..::....|.|:|.|||.:... |:.:.|.||:||.::.|..:. |..|:.|
  Fly   196 KVESY-NGSSLRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDV 259

Human   459 NITCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSAS------------------------- 498
            .:.|:|.|.||....|.:..:  .|:.::::...:..|.|                         
  Fly   260 QLECQVEASPSPVSYWLKGAR--TSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVM 322

Human   499 YLEVTPDSENDFGNYNCTAVNRIGQ 523
            .|.|...|.:|.|.|:|.:.|.:|:
  Fly   323 LLVVRSFSPSDVGTYHCVSTNSLGR 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NCAM1NP_001229536.1 Ig1_NCAM-1 20..115 CDD:143273
IG 124..190 CDD:214652
Ig 211..307 CDD:325142 19/103 (18%)
Ig 306..438 CDD:325142 37/134 (28%)
Ig_3 447..519 CDD:316449 20/97 (21%)
FN3 534..631 CDD:238020
fn3 639..720 CDD:306538
Trypan_PARP <792..>864 CDD:330686
DIP-gammaNP_651649.1 IG_like 47..139 CDD:214653 17/98 (17%)
Ig 47..129 CDD:299845 15/88 (17%)
Ig 140..238 CDD:299845 37/133 (28%)
IG_like 247..355 CDD:214653 22/102 (22%)
Ig 256..351 CDD:299845 20/93 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.910

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