DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment NCAM1 and DIP-iota

DIOPT Version :9

Sequence 1:NP_001229536.1 Gene:NCAM1 / 4684 HGNCID:7656 Length:884 Species:Homo sapiens
Sequence 2:NP_001097100.1 Gene:DIP-iota / 33925 FlyBaseID:FBgn0031837 Length:376 Species:Drosophila melanogaster


Alignment Length:338 Identity:85/338 - (25%)
Similarity:141/338 - (41%) Gaps:76/338 - (22%)


- Green bases have known domain annotations that are detailed below.


Human   132 GEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNY-------------LQIRGIKKTD 183
            |.||::.|.|...:...:.|.......||  .::..|::.|:             |:||.::::|
  Fly    45 GRDALLTCVVHDLVSFKVAWLRVDTQTIL--SIQNHVITKNHRISISHTEHRIWQLKIRDVQESD 107

Human   184 EGTYRCE-GRILARGEINFKDIQVIVNVPPTI---QARQNIVNATANLGQSVTLVCDAEGFPEPT 244
            .|.|.|: .....:.::.:.|    |.|||.|   |..|::|.:|   ||:|||.|.|.|.|.||
  Fly   108 RGWYMCQINTDPMKSQMG
YLD----VVVPPDIVDYQTSQDVVRST---GQNVTLTCSATGVPMPT 165

Human   245 MSWTK-DGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKV---- 304
            ::|.: :...|...:|.::.:||.:...||:.:|.::....|:|||.|..   ..|:..:|    
  Fly   166 ITWRREEATPILISDDGDREVFSVEGQNLTLWQVQRSHMGAYLCIASNGV---PPTVSKRVMLVV 227

Human   305 -FAKPKITYVENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQEVHAPW 368
             || |.|....:...:.|.:::||.|.....|.....|...::.:..                  
  Fly   228 NFA-PTIWTRYDTIYVGLGQKLTLECITESQPASVNFWLRDSQLLQG------------------ 273

Human   369 NWQVGRQKGQAGSAGFPGSHETLDGHMVVRSHARVSSLTLKSIQYTDAGEYICTASNTIGQDSQS 433
                             ||:|::....|.|.   |..:||:.|...|.|||||.|.|.:||..: 
  Fly   274 -----------------GSYESVSVDHVFRI---VMRITLRPITKRDFGEYICRAKNAMGQTDR- 317

Human   434 MYLEVQYAPKLQG 446
             .:.|.:..|..|
  Fly   318 -IITVHHKAKKHG 329

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NCAM1NP_001229536.1 Ig1_NCAM-1 20..115 CDD:143273
IG 124..190 CDD:214652 16/70 (23%)
Ig 211..307 CDD:325142 34/104 (33%)
Ig 306..438 CDD:325142 28/131 (21%)
Ig_3 447..519 CDD:316449 85/338 (25%)
FN3 534..631 CDD:238020
fn3 639..720 CDD:306538
Trypan_PARP <792..>864 CDD:330686
DIP-iotaNP_001097100.1 IG_like 39..125 CDD:214653 17/81 (21%)
Ig 39..122 CDD:299845 17/78 (22%)
Ig 132..213 CDD:299845 30/83 (36%)
IG_like 141..227 CDD:214653 29/91 (32%)
IG_like 239..322 CDD:214653 25/122 (20%)
IGc2 245..313 CDD:197706 22/105 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.