DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CEACAM6 and ceacam8l

DIOPT Version :9

Sequence 1:NP_002474.4 Gene:CEACAM6 / 4680 HGNCID:1818 Length:344 Species:Homo sapiens
Sequence 2:XP_031761715.1 Gene:ceacam8l / 101730286 XenbaseID:XB-GENE-22169429 Length:407 Species:Xenopus tropicalis


Alignment Length:290 Identity:96/290 - (33%)
Similarity:132/290 - (45%) Gaps:22/290 - (7%)


- Green bases have known domain annotations that are detailed below.


Human    65 YSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDL 129
            :|||||...|.|:.|...:......|.||.|..|....||.||.|..:...|.|.||:.:..::.
 Frog    58 FSWYKGSSADTNNQIFSVIPSANSVTKGPQYFPRANWLPNGSLQISGLVPTDQGNYTVLMYTAES 122

Human   130 VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLS 194
            ..:: |....||..:....||::|..|.|:: .|..||... .....||..||  :|:.|.|.||
 Frog   123 TTQD-TVSLPV
YEPVSSSGISTDNKEPQENQ-PVTLTCSAN-NAEQILWSKNG--VPLPPGLTLS 182

Human   195 NGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVPTISPSKANYRPGENLNLSC 259
            ..|.|||...:.|:|.|.|.||..|..|...|||.||.|.|||:...|. .......|.:.:|.|
 Frog   183 ADNRTLTFPRISRSDTGQYRCEASNAVSKIISDPYTLTVN
YGPENLKIK-GTLQVTSGYSTSLEC 246

Human   260 HAASNPPAQYSWFINGT-FQQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVS---- 319
            .|.|.|...|.|..||| .:..|..|:|...|..::|:|.|...||.|.|:|.|...::|:    
 Frog   247 SADSVPAPTYQWKFNGTNLESQTNTLYIQQATPESAGNYTCIGTNSVTKLSRETSVYVSVNDYNP 311

Human   320 -----GSAPVLSAVATVGITIGVLARVALI 344
                 |..|:      .||.|.::..:||:
 Frog   312 SDNPIGPGPI------AGIAIAIILVIALV 335

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CEACAM6NP_002474.4 IgV_CEACAM_D1 36..140 CDD:409430 23/74 (31%)
Ig strand B 51..55 CDD:409430
Ig strand C 64..68 CDD:409430 1/2 (50%)
Ig strand E 105..109 CDD:409430 2/3 (67%)
Ig strand F 119..124 CDD:409430 2/4 (50%)
Ig strand G 133..136 CDD:409430 0/2 (0%)
IgI_hCEACAM_2_4_6_like 146..234 CDD:409402 34/87 (39%)
Ig strand B 163..167 CDD:409402 1/3 (33%)
Ig strand C 176..180 CDD:409402 2/3 (67%)
Ig strand E 198..202 CDD:409402 2/3 (67%)
Ig strand F 212..217 CDD:409402 2/4 (50%)
Ig strand G 227..230 CDD:409402 2/2 (100%)
IgC2_CEACAM5-like 243..318 CDD:409540 24/75 (32%)
Ig strand B 255..259 CDD:409540 1/3 (33%)
Ig strand C 268..272 CDD:409540 1/3 (33%)
Ig strand E 285..289 CDD:409540 1/3 (33%)
Ig strand F 296..301 CDD:409540 2/4 (50%)
Ig strand G 311..314 CDD:409540 1/2 (50%)
ceacam8lXP_031761715.1 Ig 29..132 CDD:416386 23/74 (31%)
FR1 30..48 CDD:409353
Ig strand A 30..32 CDD:409353
Ig strand A' 37..39 CDD:409353
Ig strand B 42..49 CDD:409353
CDR1 49..56 CDD:409353
FR2 57..62 CDD:409353 2/3 (67%)
Ig strand C 57..61 CDD:409353 1/2 (50%)
CDR2 63..84 CDD:409353 4/20 (20%)
Ig strand C' 71..76 CDD:409353 1/4 (25%)
Ig strand C' 81..84 CDD:409353 0/2 (0%)
FR3 91..117 CDD:409353 10/25 (40%)
Ig strand D 91..96 CDD:409353 1/4 (25%)
Ig strand E 98..102 CDD:409353 2/3 (67%)
Ig strand F 112..117 CDD:409353 2/4 (50%)
CDR3 118..124 CDD:409353 0/5 (0%)
FR4 125..132 CDD:409353 1/7 (14%)
Ig strand G 125..131 CDD:409353 1/6 (17%)
Ig 139..222 CDD:416386 34/86 (40%)
Ig strand A 139..142 CDD:409353 0/2 (0%)
Ig strand A' 145..150 CDD:409353 2/4 (50%)
Ig strand B 154..160 CDD:409353 3/5 (60%)
Ig strand C 166..171 CDD:409353 2/4 (50%)
Ig strand C' 173..176 CDD:409353 1/2 (50%)
Ig strand D 178..182 CDD:409353 1/3 (33%)
Ig strand E 185..190 CDD:409353 3/4 (75%)
Ig strand F 200..208 CDD:409353 3/7 (43%)
Ig strand G 212..221 CDD:409353 5/8 (63%)
Ig strand A' 233..236 CDD:409353 0/2 (0%)
Ig_3 236..291 CDD:404760 18/54 (33%)
Ig strand B 241..249 CDD:409353 2/7 (29%)
Ig strand C 255..259 CDD:409353 1/3 (33%)
Ig strand C' 262..265 CDD:409353 2/2 (100%)
Ig strand E 270..275 CDD:409353 1/4 (25%)
Ig strand F 283..291 CDD:409353 3/7 (43%)
Ig strand G 294..304 CDD:409353 4/9 (44%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 49 1.000 Domainoid score I40483
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 158 1.000 Inparanoid score I12550
NCBI 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D241176at32523
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 1 1.100 - - LDO PTHR44337
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X34
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
77.070

Return to query results.
Submit another query.