Protein Alignment dlt and cdan1

DIOPT Version :10

• Sequence 1: NP_728672.1
• Gene: dlt / 46719
• FlyBaseID: FBgn0024510
• Length: 1240
• Species: Drosophila melanogaster
• Sequence 2: XP_693684.6
• Gene: cdan1 / 565314
• ZFINID: ZDB-GENE-110411-280
• Length: 1288
• Species: Danio rerio
• Alignment Length: 1136
• Identity: 283/1136 - (24%)
• Similarity: 452/1136 - (39%)
• Gaps: 267/1136 - (23%)

  Fly    23 LLAQLEKVPHHQLE-QKFVAYFKKVGKGDNQ---SNCTLEDFATYFLGALRQ------------- 70
            :.|.||.|...::| .:.|.:.|.:...::|   |..|.|:|..:.|..||.
Zfish     1 MAALLESVLQSKVELSEAVLWLKGLHVCESQNFPSRVTKEEFVPFLLNFLRDQSSQTLTHGPATP 65

  Fly    71 ----STKRYYYSQN-SETPVFPLTPIHQLK----------------------------------- 95
                ||.|....|| ||..|...||:..|:
Zfish    66 AKTPSTSRSVRIQNSSERRVSKSTPVQGLRSASRVQLFSPAPFTSPGGGKNDQDTPFTGSLCLSG 130

  Fly    96 ------PPVADVVKEEEQQQLNESSILSRSSCS--MSSTSNTTPAPQQP--QGRRSTPGSGAQFC 150
                  |..:.|.....:...:|.....|.|..  |:|...|.|:|..|  :|||.:.|.|..
Zfish   131 ISALSSPSFSSVWSPVPRNSPSERRSAQRPSLGDFMTSPPETQPSPSAPPHRGRRRSAGFGGG-- 193

  Fly   151 STPNRSGGGGA----GGGHSICLGNFLVNTPIQSHQRSK-----KKITPQKQQQNQHASLGS-GT 205
            ::..::|..||    |||                 :||:     ..::||.|.|....:|.. ..
Zfish   194 TSSRQTGARGAVSEEGGG-----------------RRSRGGGRNDSVSPQTQVQLNFNNLEDFPP 241

  Fly   206 GAGATP-QSKPRRRVLPMTIS---KNVSASSSFGDTSSFSNENNFWRISQSSEIFDRSQEAALEM 266
            .|..:| .:||.||:.|..:|   .|....|.|..| ..|...:..:|.:|:......||   |.
Zfish   242 MAQPSPIATKPSRRINPTPVSAERPNSKPKSCFTST-PLSLPASPPKIPESTGSPHNLQE---ER 302

  Fly   267 EARKFLLLKKQEIK----SEAPVNVSQQERTPE-------DEVFPEEAISL---EGVANANHLQL 317
            |     |||::..|    :.:|:..:.:..||.       .:|.|:..:..   :.|...:.|.|
Zfish   303 E-----LLKRERSKLAQQTSSPLKTNSEICTPTKTVHMQGSKVTPDSQLPCPDPDKVTQKSELDL 362

  Fly   318 LSTIYSLLMDLNLVPNVLRELSFVVHLLNVRDFGQS-------PVKSYVPSALEG--LTQHKSCV 373
            |:.:|...:..||||.:..|:.||:.||..|....|       .|....|..||.  |....:||
Zfish   363 LAGLYCACISENLVPCIFLEMFFVLQLLTSRGVSGSESAEQGISVCEDSPDVLEKAYLGNVHNCV 427

  Fly   374 YFAAKLLENQKKLLLQLDKRTLSVLLQNERLSLLPQGV---VQELETHCQRRQDSTTPFAMDTSS 435
            ||:.::||.|.:|:..|||.||.:|.:|||:......:   :.|.:.:|..:...:.|..:
Zfish   428 YFSVRVLEKQFELVSHLDKCTLRLLSENERVGTFSSSLKDCLAEAQDNCTAKVPPSPPLFV---- 488

  Fly   436 SSQQNVYYHVENDSRDNFPSQNEFGAFKSQRDLFYKALKRWEVSHLNRGFNFPSELGPRIMDIYK 500
               .:|.:....|:|.||.|...|..||.|||:||..|:.||.||...|::|.:.||.|:..:..
Zfish   489 ---HSVPFQPATDNRSNFSSDKAFHTFKKQRDVFYGLLREWEDSHKEPGWDFEAALGNRVRMMVS 550

  Fly   501 KSEHPVNMTHLAKLFVNQL--------LISATETTESPEELG-LKLDPL-RHNKLAQRLVTSSSS 555
            :.....:.:|.|:||..||        :::::......:.|| |..|.| |..:|.||||...|.
Zfish   551 QLTAAGSQSHFARLFQKQLVQMCKGPSVLASSSDAPDADLLGMLGADSLGRLKRLQQRLVQPQSL 615

  Fly   556 V----EGQFPRSQAFFRDFIAVCSSVAFLVHLKLELFVQLMR-------NNDSTFDLLQLTDDVA 609
            :    ...||..|.||:.|:...||.....|||..|..||::       ..|::....:.|.|..
Zfish   616 IGPCPPPSFPGHQEFFKGFLQTASSCQLNQHLKDGLCQQLLKLDEVSILGPDASPAQGEKTADGD 680

  Fly   610 VEEQSAQQGPYIVRVQT-MANMLILAKFLGYVTVMPFSGTTQHGNPTPPYLCPQQLQ-----LRN 668
            :|:|..:|     |..: :....:||||||::|.:|:. |::        |..:.:|     ||:
Zfish   681 MEQQDEKQ-----RFSSVLLTARLLAKFLGFITFLPYQ-TSE--------LPSRDIQDAAVALRS 731

  Fly   669 HFRPDFNLREILERSMRQGKLLITLPWLVQYLAMLDLVSLHLPDAVATLELLYGLYADI------ 727
            ...|..::..:|..|:.:.:.::|:||:|::|:|||.:...||.....|.||..:|..:
Zfish   732 KSFPVLDVCTVLRNSVHRRRTILTVPWMVEFLSMLDYIGPLLPCYRTALCLLLQIYKRMVLGRGG 796

  Fly   728 ---RMAKLQPAAVFIARSCIGWLLDAQPQLVNGYYNYRAQEAGVGSISAIVDICLKDLSCHDKSH 789
               .|.:|...||      :|||........:.:::...:|.            :|:|.....|.
Zfish   797 ELCYMNQLLMVAV------LGWLFQIPVFPEDLFFSADLKEE------------MKELENKTSSQ 843

  Fly   790 A----PLLD-ELLPVACPFLQEFR----VSITPSRQAKSGRFRYITTRLEQLQQNSSSISKDAIV 845
            .    ||:| :||...||:|.|||    ..:..|.....|..|.||....:.:..|::.|
Zfish   844 GLDTLPLVDQQLLYTCCPYLGEFRKLLAAFVAGSTSKSGGLIRKITPTSAEPRGPSTTRS----- 903

  Fly   846 ASELSPAEQQQRKLVD---AYLQSQNASTRRLIEFVTERTFKCVVKDAQQEILLP-----SKASA 902
                     ||:..||   |:..:|..|.||.:|||.||.....||..:..::|.     .|...
Zfish   904 ---------QQKLQVDLEQAFFHNQPPSLRRTVEFVAERVGSNCVKHIKATLVLELVRGGEKTLR 959

  Fly   903 D---------AKVNE-IKSTMLEEVFQELHEIFQDARENACQRWKEHVHQMLDRRIEHSLDGLLP 957
            |         ||:|: |.:.:.:...|.|....:...|||                ..::..|||
Zfish   960 DSLGMEGVNTAKLNDCICAQLCDAGMQALERATRFCSENA----------------PGAVRVLLP 1008

  Fly   958 SSTNAVLRSTYAHLIRVQAQTQLQQWLQSSV 988
            ..|:..:.:|...:....|..:...||.|::
Zfish  1009 LETSPSVLTTAKSITTRLATEKACSWLSSNI 1039

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dlt	NP_728672.1	Codanin-1_C	786..908	CDD:464622	40/147 (27%)
cdan1	XP_693684.6	PHA03378	<53..334	CDD:223065	66/308 (21%)
		Codanin-1_C	845..960	CDD:464622	36/128 (28%)