DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment arg and aru1

DIOPT Version :9

Sequence 1:	NP_524875.1	Gene:	arg / 46717	FlyBaseID:	FBgn0023535	Length:	351	Species:	Drosophila melanogaster
Sequence 2:	NP_593549.1	Gene:	aru1 / 2543377	PomBaseID:	SPAC3H1.07	Length:	323	Species:	Schizosaccharomyces pombe

Alignment Length:	321	Identity:	108/321 - (33%)
Similarity:	173/321 - (53%)	Gaps:	44/321 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LGIIGVPFAKGQAKQGVELAPDLLRQSSLRQVLQS-SHDGLVIRD---------YGNLQYAVDEP 86
            :.||.:||:.||.|.|.||||:::.::.|...|:. .:|..:|::         .|..|..:..|
pombe    24 VSIINMPFSGGQPKDGAELAPEMVEKAGLVDDLEHLGYDVKLIQNPEFKSRPSKEGPNQALMKNP 88

  Fly    87 LLQQQRVHYHHIRNYADFMACNRALIEQVKLMLVENTQFLAIGGDHAIGFGSVAGHLQHTPNLSL 151
            |         ::.|      ..|.:.:.|:..|.:....:.|||||::..|:|.|......:..:
pombe    89 L---------YVSN------VTRQVRDAVQRELEQQRVVVNIGGDHSLAIGTVEGVQAVYDDACV 138

  Fly   152 VWIDAHADINLHSTSQSGNIHGMPVSFLLEQLRNTWQHAGLQEIAP-------NCLPKDQLVYIG 209
            :|||||||||...:|.|.|:||.|:||.|          |..|..|       ..:.:.:|.:||
pombe   139 LWIDAHADINTPESSPSKNLHGCPLSFSL----------GYAEPLPEEFAWTKRVIEERRLAFIG 193

  Fly   210 LRDIDPYEAFILNKVGIRYYAMDTIDRVGVPKIIEMTLDALNP--QNKIHVSFDIDALDSNVAPS 272
            |||:||.|...|.:..|..|.|..:|:.|:.:::||.::.:||  :..:|:|||:||.|..|||:
pombe   194 LRDLDPMERAFLRERNIAAYTMHHVDKYGIGRVVEMAMEHINPGKRRPVHLSFDVDACDPIVAPA 258

  Fly   273 TGTAVRGGLTLREGISIVEALRDTKRVQGVDLVEINPKLGSERDVRTTVESGLEILKSMFG 333
            |||.|.||||.||.:.|.||:.::..:..||::|:||.||:|.:.:|||:....|:::..|
pombe   259 TGTRVPGGLTFREAMYICEAVAESGTLVAVDVMEVNPLLGNEEEAKTTVDLARSIVRTSLG 319

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
arg	NP_524875.1	Arginase	32..331	CDD:212515	107/317 (34%)
aru1	NP_593549.1	Arginase	24..313	CDD:212515	106/313 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	173	1.000	Domainoid score	I872
eggNOG	1	0.900	-	-		E1_COG0010
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	177	1.000	Inparanoid score	I1146
OMA	1	1.010	-	-		QHG56454
OrthoFinder	1	1.000	-	-		FOG0001970
OrthoInspector	1	1.000	-	-		otm47419
orthoMCL	1	0.900	-	-		OOG6_102008
Panther	1	1.100	-	-	LDO	PTHR43782
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R79
SonicParanoid	1	1.000	-	-		X1288
TreeFam	1	0.960	-	-
	13	12.860