DRSC/TRiP Functional Genomics Resources

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Protein Alignment ATF3 and kay

DIOPT Version :10

Sequence 1:NP_001665.1 Gene:ATF3 / 467 HGNCID:785 Length:181 Species:Homo sapiens
Sequence 2:NP_001027577.2 Gene:kay / 3772082 FlyBaseID:FBgn0001297 Length:755 Species:Drosophila melanogaster


Alignment Length:176 Identity:40/176 - (22%)
Similarity:60/176 - (34%) Gaps:65/176 - (36%)


- Green bases have known domain annotations that are detailed below.


Human    63 ALEEKAHV--------PMSGQSMGSQMALLANQLGRDVDNSL------NGRVDLQQFLNGQNLGI 113
            ||:..|.:        .||.|:.|..:.:...|..|:.|:.:      |.|       ||..:||
  Fly    35 ALDATAQISEIINTIGSMSAQAQGLSVPVTTAQKLRNSDHHIYLMFESNDR-------NGLVVGI 92

Human   114 MSQMSDIEDDARKNRKYPCPLCGKRFRFNSILSLHMRTHTGE-----KPFKCPYCDHRAAQKGNL 173
            :          :..||                ||::...:||     .|....:..|.:.|:|.|
  Fly    93 L----------KVGRK----------------SLYVFDPSGETVNVTAPCVLDFYVHESRQRGGL 131

Human   174 KIHLRTHKLGNLGKGRGRVREENRLLHELEERAILRDKQMKGSLLQ 219
            ...|..|.|          ||||   .:.:|.||.|..:.....||
  Fly   132 GRELFEHML----------REEN---IQPDELAIDRPSEKLLGFLQ 164

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ATF3NP_001665.1 Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 88..110 6/27 (22%)
bZIP_ATF3 96..149 CDD:269870 10/58 (17%)
coiled coil 96..146 CDD:269870 8/55 (15%)
Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 114..142 2/27 (7%)
kayNP_001027577.2 bZIP_Fos 420..481 CDD:269869
coiled coil 421..480 CDD:269869
Blue background indicates that the domain is not in the aligned region.

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