Protein Alignment NAGLU and Naglu

DIOPT Version :10

• Sequence 1: XP_024306539.1
• Gene: NAGLU / 4669
• HGNCID: 7632
• Length: 762
• Species: Homo sapiens
• Sequence 2: NP_001413972.1
• Gene: Naglu / 360630
• RGDID: 1564228
• Length: 739
• Species: Rattus norvegicus
• Alignment Length: 756
• Identity: 602/756 - (79%)
• Similarity: 669/756 - (88%)
• Gaps: 21/756 - (2%)

Human     1 MEAVAVAAAVGVLLLAGAGGAAGDEAREAAAVRALVARLLGPGPAADFSVSVERALAAKPGLDTY 65
            |.|..:||.:|.|||  |....||||:||.|||.||.|||||||||||.||||||||.:.|||||
  Rat     1 MGAAGLAAILGFLLL--ARDLVGDEAQEAEAVRELVVRLLGPGPAADFLVSVERALANESGLDTY 63

Human    66 SLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGELTEATPNRAS 130
            ||.|||...|.||||:|||||||||||||||||||:|||.|||.||.||||||..||||||||
  Rat    64 SLSGGGGVPVLVRGSSGVAAAAGLHRYLRDFCGCHIAWSSSQLHLPSPLPAVPDGLTEATPNR-- 126

Human   131 AGPPEKRKEDAYRAVLLYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQ 195
                             |||||||||.|||||||||||||:||||||||||||||||:|||||||
  Rat   127 -----------------YRYYQNVCTHSYSFVWWDWARWEQEIDWMALNGINLALAWNGQEAIWQ 174

Human   196 RVYLALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTPV 260
            ||||||||||:||:.:|||||||||||||||||||||||.|||:||||||||:||:|||||||||
  Rat   175 RVYLALGLTQSEIDNYFTGPAFLAWGRMGNLHTWDGPLPRSWHLKQLYLQHRILDRMRSFGMTPV 239

Human   261 LPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELIKEFGTD 325
            |||||||||:|:|||||||||.::|:||||||||||||||||.||:||:||:||||||.||||||
  Rat   240 LPAFAGHVPKAITRVFPQVNVIQLGNWGHFNCSYSCSFLLAPGDPLFPLIGTLFLRELTKEFGTD 304

Human   326 HIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQFWGPAQIRAVLG 390
            ||||||||||||||.|:||||||||.||||||..||.:|||||||||||||||||||:||:|||.
  Rat   305 HIYGADTFNEMQPPFSDPSYLAAATAAVYEAMVTVDPDAVWLLQGWLFQHQPQFWGPSQIKAVLE 369

Human   391 AVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGALEAVNGGPEAARLFPNS 455
            |||||||||||||||:||||:|||||.|||||||||||||||||||||||.||.||:||||||||
  Rat   370 AVPRGRLLVLDLFAETQPVYSRTASFHGQPFIWCMLHNFGGNHGLFGALEDVNQGPQAARLFPNS 434

Human   456 TMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAARRYGVSHPDAGAAWRLLLRSV 520
            ||||||:|||||.||||||:|||||||||||||||.|||:|||:||||||.|||.||||||||||
  Rat   435 TMVGTGIAPEGIGQNEVVYALMAELGWRKDPVPDLVAWVSSFASRRYGVSQPDAVAAWRLLLRSV 499

Human   521 YNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAWRLLLTSAPSLATSPAFRYDLLDLTRQ 585
            ||||||||.||||||||:||||||:|::|||||||||||||||.:||:|..||||||||||:|||
  Rat   500 YNCSGEACSGHNRSPLVKRPSLQMSTAVWYNRSDVFEAWRLLLRAAPNLTASPAFRYDLLDVTRQ 564

Human   586 AVQELVSLYYEEARSAYLSKELASLLRAGGVLAYELLPALDEVLASDSRFLLGSWLEQARAAAVS 650
            |||||||..|||||:|:|:::|..||||||:|.|:|||:|||:|||:|.||||:||:|||..|||
  Rat   565 AVQELVSSCYEEARTAFLNQDLDLLLRAGGLLTYKLLPSLDELLASNSHFLLGTWLDQAREVAVS 629

Human   651 EAEADFYEQNSRYQLTLWGPEGNILDYANKQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQ 715
            |:||.|||||||||:||||||||||||||||||||||:||.|||.|||..|..|:|:||||||||
  Rat   630 ESEAQFYEQNSRYQITLWGPEGNILDYANKQLAGLVADYYQPRWCLFLGTLAHSLARGIPFQQHQ 694

Human   716 FDKNVFQLEQAFVLSKQRYPSQPRGDTVDLAKKIFLKYYPR 756
            |:|:||.|||||:.:|:|||.||:||||||:||||||::|:
  Rat   695 FEKSVFPLEQAFINNKKRYPIQPQGDTVDLSKKIFLKFHPQ 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NAGLU	XP_024306539.1	NAGLU_N	42..115	CDD:463762	58/72 (81%)
		NAGLU	149..484	CDD:461545	293/334 (88%)
		NAGLU_C	493..747	CDD:463763	197/253 (78%)
Naglu	NP_001413972.1	None