DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(2)09851 and MSI3

DIOPT Version :9

Sequence 1:	NP_001260713.1	Gene:	l(2)09851 / 46662	FlyBaseID:	FBgn0022288	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_195231.1	Gene:	MSI3 / 829657	AraportID:	AT4G35050	Length:	424	Species:	Arabidopsis thaliana

Alignment Length:	424	Identity:	99/424 - (23%)
Similarity:	165/424 - (38%)	Gaps:	109/424 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 YLPGTKLADDEELVCDESAYVMLHQASTGAPCLSFDVIPDELGSGRQSFPMTAYIVAGTQASRAH 108
            ::|.|.:...::      .|..:|:...|.          ....|.|.|.|.|.:|..|..:...
plant    47 WVPSTPIPYSKD------PYFAVHKLILGT----------HTSGGAQDFLMVADVVIPTPDAEPG 95

  Fly   109 VNNLIVMKMSNLHKTQDNDGDEDEELEDDQDDVTDREELKKPQMTCALVKHQGCVNRVR------ 167
            :..                        .||:.:..:.|:|:.      ::..|.|||.|
plant    96 LGG------------------------RDQEPIVPKVEIKQK------IRVDGEVNRARCMPQKP 130

  Fly   168 ----ARRLGNSVYAASWSELGRVNIWDLTQPLQAVENAQLAKQYEQSEARPVFTFGGHQQEGFAI 228
                |:..|:.|:...:                    |:|:.:.:.||..|.....||:|||:.:
plant   131 TLVGAKTSGSEVFLFDY--------------------ARLSGKPQTSECDPDLRLMGHEQEGYGL 175

  Fly   229 DWSPSADGVLATGDCRRDIHVWTPVEDGTWKVDQRPL---AGHSQSVEDLQWSPNERSVLASCSV 290
            .||...:|.|.:|...:.|.:|......|.|| ..|:   .||...:||:.|.....::..|...
plant   176 AWSSFKEGYLLSGSQDQRICLWDVSATATDKV-LNPMHVYEGHQSIIEDVAWHMKNENIFGSAGD 239

  Fly   291 DKTIRIWDCRASPQKACMLTCEDAHQSDVNVISWNR-NEPFIASGGDDGYLHIWDLRQFQSKKPI 354
            |..:.|||.|.:..:..:    ..|:.::|.:|:|. ||..:|:...|..:.::|||:..:  |:
plant   240 DCQLVIWDLRTNQMQHQV----KVHEREINYLSFNPFNEWVLATASSDSTVALFDLRKLTA--PL 298

  Fly   355 ATFKHHTDHITTVEWSPAEATVLASGGDDDQIALWD--------LAVEKDIDQAVDPAQNEDVLN 411
            .....|...:..|||.|...|||||.|:|.::.:||        |.:|.|.:..
plant   299 HVLSKHEGEVFQVEWDPNHETVLASSGEDRRLMVWDINRVGDEQLEIELDAEDG----------- 352

  Fly   412 KLPPQLLFIHQGQK-EIKELHWHPQLPGVLLSTA 444
              ||:|||.|.|.| :|.:..|:...|.|:.|.|
plant   353 --PPELLFSHGGHKAKISDFAWNKDEPWVISSVA 384

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)09851	NP_001260713.1	CAF1C_H4-bd	53..120	CDD:289068	10/66 (15%)
		WD40	152..>395	CDD:295369	67/264 (25%)
		WD40	<172..>447	CDD:225201	77/286 (27%)
		WD40 repeat	226..267	CDD:293791	11/43 (26%)
		WD40 repeat	272..312	CDD:293791	9/39 (23%)
		WD40 repeat	320..357	CDD:293791	11/37 (30%)
MSI3	NP_195231.1	CAF1C_H4-bd	17..89	CDD:403473	11/57 (19%)
		WD40 repeat	121..167	CDD:293791	11/65 (17%)
		WD40	156..394	CDD:421866	73/249 (29%)
		WD40 repeat	172..209	CDD:293791	11/37 (30%)
		WD40 repeat	222..258	CDD:293791	9/39 (23%)
		WD40 repeat	264..302	CDD:293791	11/39 (28%)
		WD40 repeat	308..361	CDD:293791	21/65 (32%)
		WD40 repeat	367..392	CDD:293791	6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D831322at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920