Protein Alignment l(2)09851 and RBBP7

DIOPT Version :9

• Sequence 1: NP_001260713.1
• Gene: l(2)09851 / 46662
• FlyBaseID: FBgn0022288
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_001185648.1
• Gene: RBBP7 / 5931
• HGNCID: 9890
• Length: 469
• Species: Homo sapiens
• Alignment Length: 445
• Identity: 122/445 - (27%)
• Similarity: 197/445 - (44%)
• Gaps: 77/445 - (17%)

  Fly    32 DDTAEPKAPKEVYLPGTKLADDEELVCDESAYVMLHQASTGAPCLSFDVIPDELGSGRQSFPMTA 96
            :||.|.:...|.|....|   :...:.|   .||.|....  |.|:...:|:......:.:.: .
Human    52 EDTVEERVINEEYKIWKK---NTPFLYD---LVMTHALQW--PSLTVQWLPEVTKPEGKDYAL-H 107

  Fly    97 YIVAGTQASRAHVNNLIVMKMSNLHKTQDNDGDEDEELEDDQDD------VTDREELKKPQMTCA 155
            ::|.||..|... |:|:|   :.:|...|:...:....:.|:.:      ||.:.|       |.
Human   108 WLVLGTHTSDEQ-NHLVV---ARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIE-------CE 161

  Fly   156 L-VKHQGCVNRVRARRLGNSVYAASWSELGRVNIWDLTQPLQAVENAQLAKQYEQSEARPVFTFG 219
            : :.|:|.|||.|.......:.|.. :....|.::|.|:        ..||.....|..|.....
Human   162 IKINHEGEVNRARYMPQNPHIIATK-TPSSDVLVFDYTK--------HPAKPDPSGECNPDLRLR 217

  Fly   220 GHQQEGFAIDWSPSADGVLATGDCRRDIHVWTPVEDGT---WKVDQRP-----------LAGHSQ 270
            |||:||:.:.|:.:..|           |:.:..:|.|   |.::..|           ..|||.
Human   218 GHQKEGYGLSWNSNLSG-----------HLLSASDDHTVCLWDINAGPKEGKIVDAKAIFTGHSA 271

  Fly   271 SVEDLQWSPNERSVLASCSVDKTIRIWDCRA-SPQKACMLTCEDAHQSDVNVISWNRNEPFI-AS 333
            .|||:.|.....|:..|.:.|:.:.|||.|: :..|...|.  |||.::||.:|:|....|| |:
Human   272 VVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLV--DAHTAEVNCLSFNPYSEFILAT 334

  Fly   334 GGDDGYLHIWDLRQFQSKKPIATFKHHTDHITTVEWSPAEATVLASGGDDDQIALWDLAVEKDID 398
            |..|..:.:||||..:.|  :.||:.|.|.|..|.|||...|:|||.|.|.::.:|||:...: :
Human   335 GSADKTVALWDLRNLKLK--LHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGE-E 396

  Fly   399 QAVDPAQNEDVLNKLPPQLLFIHQGQ-KEIKELHWHPQLPGVLLSTAHSGFNIFR 452
            |:.:.|::.      ||:|||||.|. .:|.:..|:|..|.|:.|.:..  ||.:
Human   397 QSAEDAEDG------PPELLFIHGGHTAKISDFSWNPNEPWVICSVSED--NIMQ 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)09851	NP_001260713.1	CAF1C_H4-bd	53..120	CDD:289068	14/66 (21%)
		WD40	152..>395	CDD:295369	78/259 (30%)
		WD40	<172..>447	CDD:225201	87/291 (30%)
		WD40 repeat	226..267	CDD:293791	7/54 (13%)
		WD40 repeat	272..312	CDD:293791	13/40 (33%)
		WD40 repeat	320..357	CDD:293791	13/37 (35%)
RBBP7	NP_001185648.1	CAF1C_H4-bd	62..131	CDD:372002	18/81 (22%)
		WD40	166..446	CDD:392136	95/311 (31%)
		WD40 repeat	171..218	CDD:293791	11/55 (20%)
		WD40 repeat	223..267	CDD:293791	8/54 (15%)
		WD40 repeat	274..308	CDD:293791	10/33 (30%)
		WD40 repeat	319..357	CDD:293791	15/39 (38%)
		WD40 repeat	363..414	CDD:293791	22/57 (39%)
		WD40 repeat	420..445	CDD:293791	8/26 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D831322at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920