Protein Alignment l(2)09851 and RBBP4

DIOPT Version :9

• Sequence 1: NP_001260713.1
• Gene: l(2)09851 / 46662
• FlyBaseID: FBgn0022288
• Length: 456
• Species: Drosophila melanogaster
• Sequence 2: NP_005601.1
• Gene: RBBP4 / 5928
• HGNCID: 9887
• Length: 425
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 124/441 - (28%)
• Similarity: 195/441 - (44%)
• Gaps: 65/441 - (14%)

  Fly    30 AEDDTAEPKAPKEVYLPGTKLADDEELVCDESAYVMLHQASTGAPCLSFDVIPDELGSGRQSFPM 94
            |.||..|.:...|.|....|   :...:.|   .||.|....  |.|:...:||......:.|.:
Human     7 AFDDAVEERVINEEYKIWKK---NTPFLYD---LVMTHALEW--PSLTAQWLPDVTRPEGKDFSI 63

  Fly    95 TAYIVAGTQASRAHVNNLIVMKMSNLHKTQDNDGDEDEELEDDQ-------DDVTDREELKKPQM 152
            .. :|.||..|... |:|::..:    :..::|...|....|.:       ..|:.:.|::
Human    64 HR-LVLGTHTSDEQ-NHLVIASV----QLPNDDAQFDASHYDSEKGEFGGFGSVSGKIEIE---- 118

  Fly   153 TCALVKHQGCVNRVRARRLGNSVYAASWSELGRVNIWDLTQPLQAVENAQLAKQYEQSEARPVFT 217
              ..:.|:|.|||.|... .|....|:.:....|.::|.|:        ..:|.....|..|...
Human   119 --IKINHEGEVNRARYMP-QNPCIIATKTPSSDVLVFDYTK--------HPSKPDPSGECNPDLR 172

  Fly   218 FGGHQQEGFAIDWSPSADGVLATGDCRRDIHVW----TPVEDGTWKVDQRPL-AGHSQSVEDLQW 277
            ..|||:||:.:.|:|:..|.|.:......|.:|    .|.|...  ||.:.: .||:..|||:.|
Human   173 LRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKV--VDAKTIFTGHTAVVEDVSW 235

  Fly   278 SPNERSVLASCSVDKTIRIWDCRAS----PQKACMLTCEDAHQSDVNVISWNRNEPFI-ASGGDD 337
            .....|:..|.:.|:.:.|||.|::    |..:.     |||.::||.:|:|....|| |:|..|
Human   236 HLLHESLFGSVADDQKLMIWDTRSNNTSKPSHSV-----DAHTAEVNCLSFNPYSEFILATGSAD 295

  Fly   338 GYLHIWDLRQFQSKKPIATFKHHTDHITTVEWSPAEATVLASGGDDDQIALWDLAVEKDIDQAVD 402
            ..:.:||||..:.|  :.:|:.|.|.|..|:|||...|:|||.|.|.::.:|||:   .|.:...
Human   296 KTVALWDLRNLKLK--LHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLS---KIGEEQS 355

  Fly   403 PAQNEDVLNKLPPQLLFIHQGQ-KEIKELHWHPQLPGVLLSTAHSGFNIFR 452
            |...||.    ||:|||||.|. .:|.:..|:|..|.|:.|.:..  ||.:
Human   356 PEDAEDG----PPELLFIHGGHTAKISDFSWNPNEPWVICSVSED--NIMQ 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)09851	NP_001260713.1	CAF1C_H4-bd	53..120	CDD:289068	15/66 (23%)
		WD40	152..>395	CDD:295369	77/252 (31%)
		WD40	<172..>447	CDD:225201	89/285 (31%)
		WD40 repeat	226..267	CDD:293791	10/45 (22%)
		WD40 repeat	272..312	CDD:293791	12/43 (28%)
		WD40 repeat	320..357	CDD:293791	13/37 (35%)
RBBP4	NP_005601.1	CAF1C_H4-bd	19..88	CDD:403473	18/82 (22%)
		WD40	122..403	CDD:421866	97/306 (32%)
		WD 1	122..155		10/33 (30%)
		WD40 repeat	128..175	CDD:293791	11/55 (20%)
		WD 2	175..206		10/30 (33%)
		WD40 repeat	180..224	CDD:293791	11/45 (24%)
		WD 3	225..256		10/30 (33%)
		WD40 repeat	231..270	CDD:293791	11/43 (26%)
		WD 4	271..302		11/30 (37%)
		WD40 repeat	276..314	CDD:293791	14/39 (36%)
		WD 5	315..346		13/30 (43%)
		WD40 repeat	320..371	CDD:293791	24/57 (42%)
		WD 6	372..403		9/31 (29%)
		WD40 repeat	377..402	CDD:293791	8/26 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D831322at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920