DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)09851 and rba-1

DIOPT Version :9

Sequence 1:	NP_001260713.1	Gene:	l(2)09851 / 46662	FlyBaseID:	FBgn0022288	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	NP_492551.1	Gene:	rba-1 / 172801	WormBaseID:	WBGene00004312	Length:	412	Species:	Caenorhabditis elegans

Alignment Length:	392	Identity:	107/392 - (27%)
Similarity:	177/392 - (45%)	Gaps:	39/392 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 PCLSFDVIPDELGSGRQSFPMTAYIVAGTQASRAHVNNLIVMKMSNLHKTQDNDGDEDEELEDDQ 138
            |.||...:||...:......|.. ::.||.......|:|::.|.:   .|.|....:|.:.:.::
Worm    36 PSLSVQWMPDVTKTENSDSSMHR-MIHGTHTCGGVQNHLMISKFT---ITTDTPEFDDAKWDSER 96

  Fly   139 DDVTDREELKKPQMTCAL-VKHQGCVNRVRARRLGNSVYAASWSELGRVNIWDLTQPLQAVENAQ 202
            ::.....|....:....: :.|.|.|:|.|... .|....||......|.|:|.|:.
Worm    97 EEFGGYGEGSAAKWDTEIKINHPGEVHRARYMP-HNPFIIASRGPSDDVYIFDYTKH-------- 152

  Fly   203 LAKQYEQSEARPVFTFGGHQQEGFAIDWSPSADG-VLATGD----CRRDIHVWTPVEDGTWKVDQ 262
             ..:.:.::.||.....||:.||:.:.||.:.:| :|..||    |..||:....:....  |.|
Worm   153 -PSEPKDTKFRPQLRLKGHEGEGYGMSWSNTREGHLLTAGDDGMICHWDINANQTISGQI--VPQ 214

  Fly   263 RPLAGHSQSVEDLQWSPNERSVLASCSVDKTIRIWDCRAS-PQKACMLTCEDAHQSDVNVISWNR 326
            ....|||.:.||:.:......|..|...|:.:.:||.|.| ||...:     .|.::||.|::|.
Worm   215 SKFKGHSSNAEDVSFHALHNFVFGSVGDDRKLNLWDLRQSKPQLTAV-----GHTAEVNCITFNP 274

  Fly   327 -NEPFIASGGDDGYLHIWDLRQFQSKKPIATFKHHTDHITTVEWSPAEATVLASGGDDDQIALWD 390
             :|..:|:|..|..:.:||:|..  :|.:.|.|||.|.|..|.:||...|||||.|.||::.:||
Worm   275 FSEYILATGSVDKTVALWDMRNM--RKKMYTLKHHNDEIFQVSFSPHYETVLASSGSDDRVIVWD 337

  Fly   391 LAVEKDIDQAVDPAQNEDVLNKLPPQLLFIHQGQK-EIKELHWHPQLPGVLLSTAHSGFNIFRTI 454
              :.|..|.:...|.:.|   .:||:::|||.|.. ::.:..|:|..|..:.|:  ..||..:..
Worm   338 --ISKIQDPSSSSAASSD---SVPPEVIFIHAGHTGKVADFSWNPNRPWTICSS--DEFNALQVW 395

  Fly   455 SV 456
            .|
Worm   396 EV 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)09851	NP_001260713.1	CAF1C_H4-bd	53..120	CDD:289068	11/45 (24%)
		WD40	152..>395	CDD:295369	75/250 (30%)
		WD40	<172..>447	CDD:225201	84/282 (30%)
		WD40 repeat	226..267	CDD:293791	11/45 (24%)
		WD40 repeat	272..312	CDD:293791	11/40 (28%)
		WD40 repeat	320..357	CDD:293791	11/37 (30%)
rba-1	NP_492551.1	CAF1C_H4-bd	13..80	CDD:289068	11/47 (23%)
		WD40	118..>409	CDD:225201	92/306 (30%)
		WD40 repeat	123..169	CDD:293791	11/55 (20%)
		WD40	167..>398	CDD:295369	78/247 (32%)
		WD40 repeat	174..218	CDD:293791	12/45 (27%)
		WD40 repeat	225..261	CDD:293791	11/35 (31%)
		WD40 repeat	267..305	CDD:293791	13/39 (33%)
		WD40 repeat	311..364	CDD:293791	22/57 (39%)
		WD40 repeat	370..395	CDD:293791	6/26 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D831322at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920