DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)09851 and wdr59

DIOPT Version :9

Sequence 1:	NP_001260713.1	Gene:	l(2)09851 / 46662	FlyBaseID:	FBgn0022288	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	XP_009291658.1	Gene:	wdr59 / 103909113	ZFINID:	ZDB-GENE-120215-187	Length:	982	Species:	Danio rerio

Alignment Length:	244	Identity:	58/244 - (23%)
Similarity:	97/244 - (39%)	Gaps:	45/244 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 IDWSP---SADGVLATGDCRRDIHVWTPVEDGTWKVDQRPLAGHSQSVEDLQWSPNERSVLASCS 289
            :.|:|   .|....|:.:.|.|::.|   .||:.| ....|.||::.:.||.||..|...|.:.|
Zfish    65 VQWNPHKSDAHIFAASSNQRVDLYTW---RDGSGK-SHTSLQGHTRVISDLDWSWFEPEFLVTSS 125

  Fly   290 VDKTIRIWDCRASPQKACMLTCEDAHQSDVNVISWNRNEPFIASGGDDGYLHIWDLRQFQSKKPI 354
            ||..|.|||...:.:....|:.    .:..:.:.|||...:..:...||.:.|||.|  :|...:
Zfish   126 VDTYIYIWDTSDTRRPTVTLSA----VAGASQVKWNRRNHYCLASSHDGDVRIWDKR--KSNTAV 184

  Fly   355 ATFKHHTDHITTVEWSPAEATVLASGGDDDQIALWD----------LAVEKDIDQAVDPAQNEDV 409
            .....|...|..::|.|....:||:...|:.:..||          |:.:..:.:|.....:..:
Zfish   185 EYVAAHLSKINGLDWHPDNEYILATSSQDNSVRFWDYRQPRKYLDILSCQVPVWKARYTPFSNGL 249

  Fly   410 LNKLPPQL-------------------LFIHQGQKE-IKELHWHPQLPG 438
            :..:.|||                   .|:  |..: :.|..|.||..|
Zfish   250 VTVMVPQLRRENSLLLWSTLELNSPVHAFV--GHDDVVYEFQWRPQKEG 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)09851	NP_001260713.1	CAF1C_H4-bd	53..120	CDD:289068
		WD40	152..>395	CDD:295369	47/179 (26%)
		WD40	<172..>447	CDD:225201	58/244 (24%)
		WD40 repeat	226..267	CDD:293791	11/41 (27%)
		WD40 repeat	272..312	CDD:293791	14/39 (36%)
		WD40 repeat	320..357	CDD:293791	10/36 (28%)
wdr59	XP_009291658.1	WD40	<34..314	CDD:225201	58/244 (24%)
		WD40 repeat	62..103	CDD:293791	11/41 (27%)
		WD40	97..>325	CDD:295369	48/208 (23%)
		WD40 repeat	109..150	CDD:293791	14/44 (32%)
		WD40 repeat	154..187	CDD:293791	10/34 (29%)
		WD40 repeat	195..229	CDD:293791	7/33 (21%)
		WD40 repeat	237..279	CDD:293791	4/41 (10%)
		RWD	<418..484	CDD:295432
		Zn_ribbon_17	932..980	CDD:305234
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0302
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810