Protein Alignment MYOC and Myoc

DIOPT Version :10

• Sequence 1: NP_000252.1
• Gene: MYOC / 4653
• HGNCID: 7610
• Length: 504
• Species: Homo sapiens
• Sequence 2: NP_110492.2
• Gene: Myoc / 81523
• RGDID: 620430
• Length: 502
• Species: Rattus norvegicus
• Alignment Length: 500
• Identity: 406/500 - (81%)
• Similarity: 448/500 - (89%)
• Gaps: 1/500 - (0%)

Human     5 CARCCSFGPEMPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMS 69
            ||.|||.||:|||:|||.||||||.:||||||.|||||:||||||||:||||:|||||.:.||||
  Rat     4 CAYCCSCGPKMPALQLLFLACLVWGMGARTAQFRKANDRSGRCQYTFTVASPSESSCPREDQAMS 68

Human    70 VIHNLQRDSSTQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQ 134
            .|.:||||||.|..|||:||||:.||||||||:|.......||.|||||.:||.|||||||||||
  Rat    69 AIQDLQRDSSIQHADLESTKARVRSLESLLHQMTSGGVTGTQEVQEGLQGQLGALRRERDQLETQ 133

Human   135 TRELETAYSNLLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGS 199
            ||:||.||:|||||||.|||||::|.|||::||||||.||||||||||||||.|...::.:.|||
  Rat   134 TRDLEVAYNNLLRDKSALEEEKRQLEQENKDLARRLEGSSQEVARLRRGQCPSTHHPSQDMLPGS 198

Human   200 REVSTWNLDTLAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETIT 264
            ||||.|||||||||||||||||||||:||| :.||:.||.|||.|||.|:|||||:|||||||||
  Rat   199 REVSQWNLDTLAFQELKSELTEVPASQILK-NQSGHPRSKEGDKGCGVLMWVGEPVTLRTAETIT 262

Human   265 GKYGVWMRDPKPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVV 329
            |||||||||||||:|||||||||||||||.:||||||..||||.||||||||:||:.||||||||
  Rat   263 GKYGVWMRDPKPTHPYTQETTWRIDTVGTGIRQVFEYSQISQFEQGYPSKVHVLPQALESTGAVV 327

Human   330 YSGSLYFQGAESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYST 394
            |:|||||||||||||:||||||||||||||||||||||||||:|||||||||||||:||||||||
  Rat   328 YAGSLYFQGAESRTVLRYELNTETVKAEKEIPGAGYHGQFPYAWGGYTDIDLAVDESGLWVIYST 392

Human   395 DEAKGAIVLSKLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGI 459
            :|.:||||||||||||||||.|||||||||||||||:|||.|||||||:|..||:||||||.|||
  Rat   393 EENRGAIVLSKLNPENLELESTWETNIRKQSVANAFVICGILYTVSSYSSVHATINFAYDTNTGI 457

Human   460 SKTLTIPFKNRYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM 504
            |||||||||||||||||:||||||:|||||||.||||||||||:|
  Rat   458 SKTLTIPFKNRYKYSSMVDYNPLERKLFAWDNFNMVTYDIKLSEM 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYOC	NP_000252.1	COG4913	<71..>196	CDD:443941	87/124 (70%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..131		15/24 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..200		19/29 (66%)
		OLF	246..502	CDD:470611	225/255 (88%)
		Microbody targeting signal. /evidence=ECO:0000255	502..504		1/1 (100%)
Myoc	NP_110492.2	COG4372	64..>181	CDD:443500	84/116 (72%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	166..198		21/31 (68%)
		OLF	244..501	CDD:128580	226/256 (88%)