Protein Alignment MYOC and Myoc

DIOPT Version :10

• Sequence 1: NP_000252.1
• Gene: MYOC / 4653
• HGNCID: 7610
• Length: 504
• Species: Homo sapiens
• Sequence 2: NP_034995.3
• Gene: Myoc / 17926
• MGIID: 1202864
• Length: 490
• Species: Mus musculus
• Alignment Length: 490
• Identity: 401/490 - (81%)
• Similarity: 441/490 - (90%)
• Gaps: 0/490 - (0%)

Human    15 MPAVQLLLLACLVWDVGARTAQLRKANDQSGRCQYTFSVASPNESSCPEQSQAMSVIHNLQRDSS 79
            |||:.||.||||||.:||||||.|||||:||||||||:||||||||||.:.||||.|.:||||||
Mouse     1 MPALHLLFLACLVWGMGARTAQFRKANDRSGRCQYTFTVASPNESSCPREDQAMSAIQDLQRDSS 65

Human    80 TQRLDLEATKARLSSLESLLHQLTLDQAARPQETQEGLQRELGTLRRERDQLETQTRELETAYSN 144
            .|..|||:||||:.||||||||:||.:....||.|||||.:||.|||||||||||||:||.||:|
Mouse    66 IQHADLESTKARVRSLESLLHQMTLGRVTGTQEAQEGLQGQLGALRRERDQLETQTRDLEAAYNN 130

Human   145 LLRDKSVLEEEKKRLRQENENLARRLESSSQEVARLRRGQCPQTRDTARAVPPGSREVSTWNLDT 209
            ||||||.|||||::|.||||:|||||||||:||.||||||||.|:..::.:.|||||||.|||||
Mouse   131 LLRDKSALEEEKRQLEQENEDLARRLESSSEEVTRLRRGQCPSTQYPSQDMLPGSREVSQWNLDT 195

Human   210 LAFQELKSELTEVPASRILKESPSGYLRSGEGDTGCGELVWVGEPLTLRTAETITGKYGVWMRDP 274
            ||||||||||||||||:||||:|||..||.|||.|||.|||||||:||||||||.||||||||||
Mouse   196 LAFQELKSELTEVPASQILKENPSGRPRSKEGDKGCGALVWVGEPVTLRTAETIAGKYGVWMRDP 260

Human   275 KPTYPYTQETTWRIDTVGTDVRQVFEYDLISQFMQGYPSKVHILPRPLESTGAVVYSGSLYFQGA 339
            |||:|||||:|||||||||::||||||..||||.||||||||:|||.|||||||||:||||||||
Mouse   261 KPTHPYTQESTWRIDTVGTEIRQVFEYSQISQFEQGYPSKVHVLPRALESTGAVVYAGSLYFQGA 325

Human   340 ESRTVIRYELNTETVKAEKEIPGAGYHGQFPYSWGGYTDIDLAVDEAGLWVIYSTDEAKGAIVLS 404
            |||||:||||:|||||||||||||||||.|||:|||||||||||||:||||||||:|||||||||
Mouse   326 ESRTVVRYELDTETVKAEKEIPGAGYHGHFPYAWGGYTDIDLAVDESGLWVIYSTEEAKGAIVLS 390

Human   405 KLNPENLELEQTWETNIRKQSVANAFIICGTLYTVSSYTSADATVNFAYDTGTGISKTLTIPFKN 469
            ||||.|||||:|||||||||||||||:|||.|||||||:||.|||||||||.||.||||||||.|
Mouse   391 KLNPANLELERTWETNIRKQSVANAFVICGILYTVSSYSSAHATVNFAYDTKTGTSKTLTIPFTN 455

Human   470 RYKYSSMIDYNPLEKKLFAWDNLNMVTYDIKLSKM 504
            ||||||||||||||:|||||||.|||||||||.:|
Mouse   456 RYKYSSMIDYNPLERKLFAWDNFNMVTYDIKLLEM 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYOC	NP_000252.1	COG4913	<71..>196	CDD:443941	88/124 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..131		15/24 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	170..200		18/29 (62%)
		OLF	246..502	CDD:470611	225/255 (88%)
		Microbody targeting signal. /evidence=ECO:0000255	502..504		0/1 (0%)
Myoc	NP_034995.3	COG4372	51..>168	CDD:443500	85/116 (73%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..184		19/30 (63%)
		OLF	232..489	CDD:128580	226/256 (88%)