Protein Alignment Naglu and naglu

DIOPT Version :10

• Sequence 1: NP_652045.1
• Gene: Naglu / 46386
• FlyBaseID: FBgn0014417
• Length: 778
• Species: Drosophila melanogaster
• Sequence 2: XP_688608.4
• Gene: naglu / 560126
• ZFINID: ZDB-GENE-100726-2
• Length: 757
• Species: Danio rerio
• Alignment Length: 764
• Identity: 302/764 - (39%)
• Similarity: 441/764 - (57%)
• Gaps: 39/764 - (5%)

  Fly    10 ALLAVLCLQLAQGSELNWDAASGPEMGLQMAAHLAPSTPKDVQETAAMAVISRVIGERSSQLFKV 74
            ||:|:|.:.|..       :..|   ..|..|||........|..|.:.::.|::|.|:.: |.|
Zfish     8 ALIALLFMTLLH-------SVCG---DFQTLAHLRAKASDKSQSRAVLDLLRRLLGNRARE-FIV 61

  Fly    75 QVNKNMDLRSFQISML---DDGRILLMGWDGVSVCKALHHYLKYVLNKDVDWFKMRIELPTNLQL 136
            .||:.:......:..|   .:.:::.:|..||:|...:::||||..|..|.|...::.||.  .|
Zfish    62 SVNRTLSADGLDVCELRSAKNNKVVAVGSTGVAVATGIYNYLKYFCNCHVSWAGDQLNLPR--PL 124

  Fly   137 PNVTIESKSASP--IIYHQNVCTWSYSFAWWGIEQWRRHLDWMALMGISLTIA-PVQEAIWVKVY 198
            |.:|...:.::|  ..|:|||||.|||..||...:|:|.:|||||.||:|.:| ..||.:|.:||
Zfish   125 PALTGVLRISTPHRFRYYQNVCTASYSSVWWDWPRWQREIDWMALNGINLPLAFTGQEVLWQEVY 189

  Fly   199 TDMGLRMEEIDEHLAGPAFQAWQRMGNIRGWAGPLTPAWRRYQLLLQQEIITAQRNLGMSVALPA 263
            ..:||...|:|...:||||.||.||||:..|.|||..:|...||.||.:|:...|:.||...|||
Zfish   190 LSLGLNQTELDRFFSGPAFLAWNRMGNLFQWGGPLPQSWHVKQLYLQFKILDRMRSFGMIPVLPA 254

  Fly   264 FAGHVPRALKRLNPESTFMEVQRWNQFPDRYCCGLFVEPTENLFKEIASRFLHNIITKYGSNHIF 328
            |:|.||..:.||.|::...::..|:.|...|.|...::|.:.||..|.:.||..:|.::|::||:
Zfish   255 FSGIVPEGITRLFPKANVTKLSPWSHFNCTYSCAYVLDPRDPLFHRIGALFLTQVIEEFGTDHIY 319

  Fly   329 FCDPFNELEPPVAKPEYMRSTAAAIYESMRGIDPQAIWLLQGWMFVKNP-FWTTDMAEAFLTAAP 392
            ..|.|||:.|..:.|.|:.|.:.||:.:|..:|||||||:|||:|:.:| ||..|..:|.|...|
Zfish   320 NTDTFNEMPPASSDPTYLASISRAIFNTMTSVDPQAIWLMQGWLFISDPSFWKADQVKALLHGVP 384

  Fly   393 RGRILVLDLQSEQFPQYELTRSYFGQPFIWCMLHNFGGTLGMFGSAKLINSGIEEARRLPNSSLV 457
            .||::||||.:|..|.|..|.|::||||||||||||||..|:||:...||||...|.|.|||:||
Zfish   385 LGRMIVLDLFAESMPVYSSTNSFYGQPFIWCMLHNFGGNSGLFGTVDSINSGPFNAVRFPNSTLV 449

  Fly   458 GTGITPEGIGQNYVMYSFTLERGWSNTSLDLDSWFTNFSHSRYGVKDERLEQAWLLLKNSVYSFR 522
            |.|:|||||.||.|:|....|..|....::|..|.:.::..|||..||.|..||.||..|||:..
Zfish   450 GLGMTPEGIEQNPVIYELMSELAWRKDPVNLYKWVSLYALRRYGSMDENLALAWQLLFRSVYNCT 514

  Fly   523 GLQKMR--GQYVVTRRPSFNQEPFTWYNASAVLDAWHLLLTFRA---IIPLEDNRYEIYEHDLVD 582
             |.|.:  .:..:..|||.:.:...||:.:....||.||  |.|   ::.||..||     ||||
Zfish   515 -LPKYKNHNRSPLVHRPSLHMQTDIWYDPADFYRAWKLL--FEAAPGLVTLETFRY-----DLVD 571

  Fly   583 ITRQFLQISADQLYINLRSAYRKRQVSRFEFLS---VKLLKLFDDMELILASSRNFLLGNWLQQA 644
            :|||.||:...:.|.:::||::.:::|  :.|:   |.:..|..:::.||:|:.:||||.|||||
Zfish   572 VTRQALQLLTTEFYKDIKSAFQTQKLS--DLLTAGGVLVYDLLPELDRILSSNEHFLLGAWLQQA 634

  Fly   645 KQAAPNTGQQRNFEFNARNQITAWGPDGQILDYACKQWSGLVSDYYRPRWRLFLEDVTVALHAGR 709
            :....:..:...::.|||||||.|||:|:|||||.|:|:|||.|||..||.||:..:...|..||
Zfish   635 QSQGVDEHEAHLYDINARNQITLWGPNGEILDYASKEWAGLVEDYYLQRWGLFVNTLVECLDRGR 699

  Fly   710 PFNGTAFKLKVSHEIELPFSNKDDVYPVTPVGNTWLISQDIFETWKGYS 758
            ||....|...| .::|..|......||..|:|:|:.|::.||..:..|:
Zfish   700 PFKQDVFNQAV-FQVEKGFVFNQRKYPTKPLGDTYDIARRIFLKYYPYA 747

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naglu	NP_652045.1	NAGLU_N	54..134	CDD:463762	22/82 (27%)
		NAGLU	151..483	CDD:461545	159/333 (48%)
		NAGLU_C	491..748	CDD:463763	102/264 (39%)
naglu	XP_688608.4	None