| Sequence 1: | XP_024309300.1 | Gene: | MYLK / 4638 | HGNCID: | 7590 | Length: | 1924 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_647461.3 | Gene: | Mylk / 107589 | MGIID: | 894806 | Length: | 1950 | Species: | Mus musculus |
| Alignment Length: | 1960 | Identity: | 1644/1960 - (83%) |
|---|---|---|---|
| Similarity: | 1743/1960 - (88%) | Gaps: | 54/1960 - (2%) |
- Green bases have known domain annotations that are detailed below.
|
Human 4 GQLPKQTMGDVKLVASSHISKTSLSVDPSRVDSMPLTEAPAFILPPRNLCIKEGATAKFEGRVRG 68
Human 69 YPEPQVTWHRNGQPITSGGRFLLDCGIRGTFSLVIHAVHEEDRGKYTCEATNGSGARQVTVELTV 133
Human 134 EGSFAKQLGQPVVSKTLGDRFSAPAVETRPSIWGECPPKFATKLGRVVVKEGQMGRFSCKITGRP 198
Human 199 QPQVTWLKGNVPLQPSARVSVSEKNGMQVLEIHGVNQDDVGVYTCLVVNGSGKASMSAELSIQGL 263
Human 264 DSANRSFVRETKATNSDVRKEVTNVISKESKLDSLEAAAKSKNCSSPQRGGSPPWAANSQPQPPR 328
Human 329 ESKLESCKDSPRTAPQTPVLQKTSSSITLQAARVQPEPRAPGLGVLSPSGEERKRPAPPRPATFP 393
Human 394 TRQPGLGSQDVVSKAANRRIPMEGQRDSAFPKFESKPQSQEVKENQTVKFRCEVSGIPKPEVAWF 458
Human 459 LEGTPVRRQEGSIEVYEDAGSHYLCLLKARTRDSGTYSCTASNAQGQLSCSWTLQVERLAVMEVA 523
Human 524 PSFSSVLKDCAVIEGQDFVLQCSVRGTPVPRITWLLNGQPIQYARSTCEAGVAELHIQDALPEDH 588
Human 589 GTYTCLAENALGQVSCSAWVTVHEKKSSRKSEYLLPVAPSKPTAPIFLQGLSDLKVMDGSQVTMT 653
Human 654 VQVSGNPPPEVIWLHNGNEIQESEDFHFEQRGTQHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQA 718
Human 719 VLTVQEPHDGTQPWFISKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALCKDTGHFEVLQN 783
Human 784 EDVFTLVLKKVQPWHAGQYEILLKNRVGECSCQVSLMLQNSSARALPRGREPASCEDLC-GGGVG 847
Human 848 ADGGGSDRYGSLRPGWPARGQGWLEEEDGEDVRGVLKRRVETRQHTEEAIRQQEVEQLDFRDLLG 912
Human 913 KKVSTKTLSEDDLKEIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTSKTPV 977
Human 978 PEKVPPPKPATPDFRSVLGGKKKLPAENGSSSAETLNAKAVESSKPLSNAQPSGPLKPVGNAKPA 1042
Human 1043 ETLKPMGNAKPAETLKPMGNAKPDENL------------------------------------KS 1071
Human 1072 ASKEELKKDVKNDVNCKRGHAGTTDNEKRSESQGTAPAFKQKLQDVHVAEGKKLLLQCQVSSDPP 1136
Human 1137 ATIIWTLNGKTLKTTKFIILSQEGSLCSVSIEKALPEDRGLYKCVAKNDAGQAECSCQVTVDDAP 1201
Human 1202 ASENTKAPEMKSRRPKSSLPPVLGTESDATVKKKPAPKTPPKAAMPPQIIQFPEDQKVRAGESVE 1266
Human 1267 LFGKVTGTQPITCTWMKFRKQIQESEHMKVENSENGSKLTILAARQEHCGCYTLLVENKLGSRQA 1331
Human 1332 QVNLTVVDKPDPPAGTPCASDIRSSSLTLSWYGSSYDGGSAVQSYSIEIWDSANKTWKELATCRS 1396
Human 1397 TSFNVQDLLPDHEYKFRVRAINVYGTSEPSQESELTTVGEKPEEPKDEVEVSDDDEKEPEVDYRT 1461
Human 1462 VTINTEQKVSDFYDIEERLGSGKFGQVFRLVEKKTRKVWAGKFFKAYSAKEKENIRQEISIMNCL 1526
Human 1527 HHPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIHKQGI 1591
Human 1592 VHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEPIGYATDMWS 1656
Human 1657 IGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISDDAKDFISNLLKKDMKNRLDCT 1721
Human 1722 QCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGRLSSMAMISGLSGRKSSTGS 1786
Human 1787 PTSPLNAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRDLEVVEGSAARFDCKIEGYPDPEVV 1851
Human 1852 WFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDDAKYTCKAVNSLGEATCTAELIVETMEEGE 1916
Human 1917 GE--GEEEEE 1924 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MYLK | XP_024309300.1 | I-set | 43..133 | CDD:254352 | 80/89 (90%) |
| I-set | 171..260 | CDD:254352 | 79/88 (90%) | ||
| 23ISL | 261..422 | CDD:318761 | 82/160 (51%) | ||
| I-set | 424..514 | CDD:254352 | 69/89 (78%) | ||
| I-set | 524..610 | CDD:254352 | 73/85 (86%) | ||
| I-set | 633..722 | CDD:254352 | 83/88 (94%) | ||
| I-set | 731..819 | CDD:254352 | 81/87 (93%) | ||
| I-set | 1108..1197 | CDD:254352 | 76/88 (86%) | ||
| Ig8_hMLCK_like | 1248..1345 | CDD:143239 | 89/96 (93%) | ||
| FN3 | 1341..1433 | CDD:238020 | 83/91 (91%) | ||
| STKc_MLCK1 | 1471..1729 | CDD:271093 | 253/257 (98%) | ||
| I-set | 1819..1909 | CDD:254352 | 89/89 (100%) | ||
| Mylk | NP_647461.3 | I-set | 42..132 | CDD:254352 | 80/89 (90%) |
| Ig | 42..131 | CDD:299845 | 79/88 (90%) | ||
| I-set | 165..254 | CDD:254352 | 79/88 (90%) | ||
| Ig | 183..251 | CDD:143165 | 59/67 (88%) | ||
| 23ISL | 255..409 | CDD:293226 | 82/160 (51%) | ||
| I-set | 411..501 | CDD:254352 | 69/89 (78%) | ||
| Ig | 428..498 | CDD:143165 | 54/69 (78%) | ||
| I-set | 511..597 | CDD:254352 | 73/85 (86%) | ||
| IGc2 | 524..587 | CDD:197706 | 54/62 (87%) | ||
| I-set | 620..709 | CDD:254352 | 83/88 (94%) | ||
| Ig | 637..706 | CDD:143165 | 63/68 (93%) | ||
| I-set | 718..806 | CDD:254352 | 81/87 (93%) | ||
| Ig | 721..806 | CDD:299845 | 78/84 (93%) | ||
| I-set | 1129..1218 | CDD:254352 | 76/88 (86%) | ||
| IGc2 | 1142..1208 | CDD:197706 | 55/65 (85%) | ||
| Ig | 1269..1366 | CDD:299845 | 89/96 (93%) | ||
| I-set | 1269..1358 | CDD:254352 | 81/88 (92%) | ||
| FN3 | 1362..1453 | CDD:238020 | 82/90 (91%) | ||
| STKc_MLCK1 | 1492..1750 | CDD:271093 | 253/257 (98%) | ||
| Pkinase | 1495..1750 | CDD:278497 | 251/254 (99%) | ||
| I-set | 1840..1930 | CDD:254352 | 89/89 (100%) | ||
| IGc2 | 1853..1920 | CDD:197706 | 66/66 (100%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83967414 | |
| Domainoid | 1 | 1.000 | 520 | 1.000 | Domainoid score | I6980 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0613 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H14202 | |
| Inparanoid | 1 | 1.050 | 3246 | 1.000 | Inparanoid score | I505 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG41176 | |
| OrthoDB | 1 | 1.010 | - | - | D10522at32523 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0007119 | |
| OrthoInspector | 1 | 1.000 | - | - | oto113899 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_104679 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR47633 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R4882 |
| SonicParanoid | 1 | 1.000 | - | - | X3431 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| 18 | 18.300 | |||||