Protein Alignment MYL2 and mlc-2

DIOPT Version :10

• Sequence 1: NP_000423.2
• Gene: MYL2 / 4633
• HGNCID: 7583
• Length: 166
• Species: Homo sapiens
• Sequence 2: NP_510828.1
• Gene: mlc-2 / 181775
• WormBaseID: WBGene00003370
• Length: 170
• Species: Caenorhabditis elegans
• Alignment Length: 166
• Identity: 78/166 - (46%)
• Similarity: 111/166 - (66%)
• Gaps: 5/166 - (3%)

Human     2 APKKAKKRAGGANSNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEI 66
            |.||:.|:..|:.:   :.|:|..||||||||.|||||:||.|||:||:|.:|::|:: ..:.:|
 Worm     5 AKKKSSKKRSGSEA---AQFDQKTIQEFKEAFGIMDQNKDGIIDKSDLKDLYASMGQI-APDSQI 65

Human    67 DEMIKEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKA-DYVREMLTTQAERF 130
            |.|||||.||||||||||:|||:|.|.|||.||:.||.:||.:..|.:|. |.::.:...:.|..
 Worm    66 DAMIKEASGPINFTVFLTLFGERLTGTDPEATIVGAFAMFDKKDCGKIKEDDLIKILQNKRGEPL 130

Human   131 SKEEVDQMFAAFPPDVTGNLDYKNLVHIITHGEEKD 166
            .::||..|:...||...|.:|||...|:||.|.:.:
 Worm   131 DEDEVKAMYKGKPPIEGGEVDYKAFAHLITTGAQDE 166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MYL2	NP_000423.2	PTZ00184	20..160	CDD:185504	70/140 (50%)
mlc-2	NP_510828.1	PTZ00184	18..160	CDD:185504	70/145 (48%)