Protein Alignment l(2)dtl and Ahi1

DIOPT Version :10

• Sequence 1: NP_524871.1
• Gene: l(2)dtl / 46326
• FlyBaseID: FBgn0013548
• Length: 769
• Species: Drosophila melanogaster
• Sequence 2: XP_063119077.1
• Gene: Ahi1 / 308923
• RGDID: 1303040
• Length: 1108
• Species: Rattus norvegicus
• Alignment Length: 790
• Identity: 167/790 - (21%)
• Similarity: 269/790 - (34%)
• Gaps: 245/790 - (31%)

  Fly    43 YCPDFNPEPPIFSAKFANCDGYRHILAIANEDGKITLQDTTQRNHQPEEQSLVGPQCHFNAVFDL 107
            :|.||:....|.:|..|:.||| .|:......|:..             :.|.|   |.|.::||
  Rat   464 FCLDFSHNGRILAAACASRDGY-PIILYEIPSGRFM-------------RELCG---HLNIIYDL 511

  Fly   108 EWAPGQMRFVSASGDHTARLWEVAGSGIRGLNSY--VGHTRSVKSAAFKRTDPAVFATGGRDGAI 170
            :|:......|::|.|.|||:|:   :.|...:::  :.|...|.:|.|......:..||..|..|
  Rat   512 DWSKDDRYLVTSSSDGTARVWK---NEINSTSTFRVLPHPSFVYTARFHPATRELVVTGCYDSMI 573

  Fly   171 LIWDIRANLNMDLTSRVDNCIYSGHTGGPGTPVSQRKQRTRTPKMAGGTTSSSITGLAFQDNDTL 235
            .||.:.|        |.|..|.          |.|.           ....|.:..:.|.|....
  Rat   574 RIWKVDA--------REDAAIL----------VRQL-----------DVHKSFVNSICFDDEGHH 609

  Fly   236 ISCGAGDGVIKVWDLRRNYTAYKKEPLPRHKLPY------AGSSTFRG--FTNLIVDASGTRLYA 292
            :..|...|||.|||      .|.|....:|.:.:      ...:.|||  .:.|.|..:|.||..
  Rat   610 MYSGDCIGVIAVWD------TYVKVTDVQHSVRHWTINKEIKETEFRGVPVSYLEVHPNGKRLLI 668

  Fly   293 NCMDNTIYCYNLASYSQRPLACYK--GLLNSTFYIKSCLSPDGKYLLSGSSDERAYIWNLD---- 351
            :..|:|:...:|     |.||..|  |..|....|.|.|:|.|..|.|||.|...|:||.:
  Rat   669 HTKDSTLRIMDL-----RILAARKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETGEQ 728

  Fly   352 ---HAEEPLVA----LAGHTVE--VTCVAWGSSHDCPIVTCSDDARHKIWRIGPDLDGLSEAERA 407
               ::|.|..:    ::.|..|  |...|:|.|.  ||:....|     :::..     .|||..
  Rat   729 VAMYSELPFKSTIRDISYHPFENMVAFCAFGQSE--PILLYIYD-----FQVAQ-----QEAEML 781

  Fly   408 EKYRGTASYVREFGKKAFGPSSGNHKYNLRDLESTPRSLKRLMDQNERTPGSVEKTTTKRSFLEM 472
            ::|.||.            |..|.|                   |:|....:..|...:.||
  Rat   782 KRYSGTV------------PLPGIH-------------------QSEDALCTCPKLPQQGSF--- 812

  Fly   473 LGVAGQETEATEQPQKRAKPLESRGRRLFGPSSQETACRHIQ-----LQSINEEDASPSKRQKEN 532
                 |..|..                    :::..:.|.||     |:::.|...|.:.:..:|
  Rat   813 -----QIDEFV--------------------NTENNSSRKIQLVKQRLETVTEVIRSCAAKVNKN 852

  Fly   533 SAAEDVSPLHKLLSTPSHSP--------LSENVNHVYTSPPTTSAAAAAVAAD------ALNPPP 583
            .:.....|      .|:..|        .::.:.|.:..|.|     |.::.:      .::|||
  Rat   853 LSITSPPP------GPAKKPRVKQSFVLTTDQIIHQFGVPQT-----AFISIERRPFMRPVDPPP 906

  Fly   584 ISAAIYSPTSNLPN------------YVLDGE----------------APHLGIMSPKR----KA 616
            :..|:|..|::..:            :..|.|                |.|:...:..|    |.
  Rat   907 MVVALYDYTASRSDELTIHRGDIIRVFFKDNEDWWYGSLGKGQEGFFPANHVASETLYRDSPPKV 971

  Fly   617 KEKVDWLTNIRKQKLMSGRAHVTLSEKISEEQQADVLASPRLQSLRQSECSPRIHASPRRRISHT 681
            ||:...||...|.|:          ||....::..::....|.|        |:.:.|   :.|:
  Rat   972 KERSPPLTPKEKAKM----------EKPPASRKQSLIKDRFLDS--------RLGSKP---MGHS 1015

  Fly   682 DGGGGTPAGSSSHSHSQSQPKTPTSSRRNSETTLLRF-FSIQRSSSVPAEETTTTNAAPSSSDP- 744
            :.|.........|.......|:..:.|:   .||:.. .:.|:.||...||....:....:..|
  Rat  1016 EKGRDQNFEERGHKSDMEMKKSEPTVRK---VTLIEVRENQQKGSSERKEEEVIPSPRTHARQPG 1077

  Fly   745 -HPPAVTAPA 753
             |.|..|..|
  Rat  1078 LHMPESTGLA 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(2)dtl	NP_524871.1	WD40	52..393	CDD:475233	93/365 (25%)
		WD40 repeat	53..99	CDD:293791	10/45 (22%)
		WD40 repeat	105..143	CDD:293791	11/39 (28%)
		WD40 repeat	148..212	CDD:293791	15/63 (24%)
		WD40 repeat	220..263	CDD:293791	12/42 (29%)
		WD40 repeat	270..316	CDD:293791	14/47 (30%)
		WD40 repeat	324..361	CDD:293791	15/47 (32%)
		WD40 repeat	367..392	CDD:293791	7/24 (29%)
Ahi1	XP_063119077.1	None