Protein Alignment ZFHX3 and CG5708

DIOPT Version :10

• Sequence 1: XP_054236368.1
• Gene: ZFHX3 / 463
• HGNCID: 777
• Length: 3704
• Species: Homo sapiens
• Sequence 2: NP_609359.1
• Gene: CG5708 / 34361
• FlyBaseID: FBgn0032196
• Length: 241
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 49/252 - (19%)
• Similarity: 76/252 - (30%)
• Gaps: 88/252 - (34%)

Human   519 SKKDLALSNQSISNSP--LMPNVL----QTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSEGV 577
            |.:|:..::...|:||  ..|.|:    ...::.|..|:||.:||
  Fly     7 SYRDILAAHHQDSSSPENFAPIVIDYRNSNHTKDTVETNSNISSS-------------------- 51

Human   578 RANVAEGGRRLDFADESANKDNATAPEPNESTEGDDGGFVPHHQHAGSLCELGVGECPSGSGVEC 642
                     :|.|.|||:|..|      |:..           .|:.||.::            |
  Fly    52 ---------QLSFMDESSNDFN------NQQL-----------IHSNSLIKV------------C 78

Human   643 PKCDTVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSC------ 701
            ..|...:.....|.......|  |.|  |||..|.              ....|.|.||
  Fly    79 GGCGDKISDRYLLYALDRYWH--NGC--LKCHCCG--------------AMLAEVGSSCFTRRGL 125

Human   702 VYCKSGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQ 758
            :.||..........|....||......|:...:.|...|:.:..|..:.:|.:.:|:
  Fly   126 ILCKKDYSSMFGCSGVCSGCGETIPPSELVAKALTGINNIDLQNQQKQIINCVFHLR 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZFHX3	XP_054236368.1	C2H2 Zn finger	673..693	CDD:275368	2/19 (11%)
		C2H2 Zn finger	728..745	CDD:275368	3/16 (19%)
		C2H2 Zn finger	1362..1385	CDD:275368
		C2H2 Zn finger	1403..1423	CDD:275371
		C2H2 Zn finger	1431..1452	CDD:275371
		C2H2 Zn finger	1547..1571	CDD:275368
		C2H2 Zn finger	1598..1616	CDD:275368
		HOX	2145..2201	CDD:197696
		Homeodomain	2243..2299	CDD:459649
		COG5576	2594..2738	CDD:227863
		Homeodomain	2642..2698	CDD:459649
		Homeodomain	2947..3003	CDD:459649
		Herpes_BLLF1	<3104..>3191	CDD:282904
CG5708	NP_609359.1	LIM1_LMO4	78..132	CDD:188772	16/71 (23%)
		LIM	142..212	CDD:413332	8/41 (20%)