Sequence 1: | NP_002464.1 | Gene: | MYH9 / 4627 | HGNCID: | 7579 | Length: | 1960 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001285949.1 | Gene: | ck / 34882 | FlyBaseID: | FBgn0000317 | Length: | 2167 | Species: | Drosophila melanogaster |
Alignment Length: | 2128 | Identity: | 550/2128 - (25%) |
---|---|---|---|
Similarity: | 905/2128 - (42%) | Gaps: | 443/2128 - (20%) |
- Green bases have known domain annotations that are detailed below.
Human 32 VWVPSDKSGFEPASLKE-EVGEEAIVELVENGKKVKVNKDD-----------IQKMNPPKFSKVE 84
Human 85 DMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVEMYKGKKRHEMPPH 149
Human 150 IYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQA 214
Human 215 NPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYY 279
Human 280 LLSGAGEHLKTDLLLEPYNKYRFLSNGH-VTIPGQQDKDMFQETMEAMRIMGIPEEEQMGLLRVI 343
Human 344 SGVLQLGNIVFKKE--RNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQT 406
Human 407 KEQADFAIEALAKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLNSFEQLCINY 471
Human 472 TNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALLDEECWFPK 536
Human 537 ATDKSFVEKVMQEQGTHPKFQKPKQLKDKADFCIIHYAGKVDYKADEWLMKNMDPLNDNIATLLH 601
Human 602 QSSDKFVSELW-KDVDRIIGLDQVAGMSETALPGAFKTRKGMFRTVGQLYKEQLAKLMATLRNTN 665
Human 666 PNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYEILTPNSIP 730
Human 731 KGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERDLKITDVIIGFQACCRGYLA 795
Human 796 RKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRL-FTKVKPLLQ-------------------- 839
Human 840 -----VSRQE--EEMMAKEEELVKVRE--KQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETEL 895
Human 896 CAEAEELRARLTAKKQELEE-----ICHDLEAR-VEEEEERCQHLQAEKKKMQQNIQELEEQLEE 954
Human 955 EESARQKLQ-LEKVTTEAKLKKLEEEQIILED----QNCKLAKEKKLLEDRIAEFTTNLTEEEEK 1014
Human 1015 ------------------SKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGD----- 1056
Human 1057 --STDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQK-----------NMALKKIRE 1108
Human 1109 LESQI-SELQED----------LESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQ--- 1159
Human 1160 -ELRSKR-----------------EQEVNILKKTLEEEAKTHEAQIQEMRQK------HSQAVEE 1200
Human 1201 LAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQE-LQVKFNEG 1264
Human 1265 ERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALES----QLQDTQELL---QEENR 1322
Human 1323 QKLSLSTKLKQVEDEKNSFREQLEEEEE---------------------------------AKHN 1354
Human 1355 LEKQIATLHAQVADMKKK---MEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAY----DKLE 1412
Human 1413 K---------TKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLA------EEKTISAKYAE 1462
Human 1463 E-RDRA-----EAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEME-DLMSSKDD-VGKS 1519
Human 1520 VHE----LEKSKRALE------QQVEEMKTQLEELEDEL------QATEDAKLRLEVNLQAM--- 1565
Human 1566 ------------------KAQFERDLQGRDEQSEEK--------KKQLVRQVREMEAELEDERKQ 1604
Human 1605 RSMAVAARKKLEMDL--------KDLEAHI-DSANKN---RDEAIKQLRKLQAQMKDCMRELDDT 1657
Human 1658 RA--------------------------SREEILAQ---------AKENEKKLKSMEAEMIQLQE 1687
Human 1688 -------------------ELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQ 1733
Human 1734 LEEELEEEQGN-----TELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVK 1793
Human 1794 L-QEMEGTVKSKYKASITALEAKIAQLEEQLD-NETKERQAACKQVRR 1839 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
MYH9 | NP_002464.1 | Mediates interaction with LIMCH1. /evidence=ECO:0000269|PubMed:28228547 | 2..838 | 309/822 (38%) | |
Myosin_N | 29..68 | CDD:367160 | 11/36 (31%) | ||
Motor_domain | 95..764 | CDD:354959 | 269/672 (40%) | ||
Actin-binding | 654..676 | 11/21 (52%) | |||
Myosin_tail_1 | 841..1921 | CDD:366712 | 240/1277 (19%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1035..1057 | 5/28 (18%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1118..1137 | 6/28 (21%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1877..1960 | ||||
ck | NP_001285949.1 | MYSc | 64..733 | CDD:214580 | 279/697 (40%) |
MYSc_Myo7 | 77..721 | CDD:276832 | 269/672 (40%) | ||
MyTH4 | <1138..1245 | CDD:214535 | 21/120 (18%) | ||
B41 | 1251..1467 | CDD:214604 | 39/222 (18%) | ||
FERM_B-lobe | 1355..1439 | CDD:271216 | 10/83 (12%) | ||
FERM_C1_MyoVII | 1461..1559 | CDD:270019 | 22/100 (22%) | ||
SH3 | 1560..1624 | CDD:302595 | 15/74 (20%) | ||
MyTH4 | 1701..1849 | CDD:214535 | 28/154 (18%) | ||
B41 | 1856..2068 | CDD:214604 | 35/173 (20%) | ||
FERM_M | 1966..2068 | CDD:278785 | 13/50 (26%) | ||
FERM_C2_MyoVII | 2064..2159 | CDD:270020 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |