DRSC/TRiP Functional Genomics Resources

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Protein Alignment Pglym87 and PGAM2

DIOPT Version :9

Sequence 1:NP_652041.2 Gene:Pglym87 / 46246 FlyBaseID:FBgn0011270 Length:292 Species:Drosophila melanogaster
Sequence 2:NP_000281.2 Gene:PGAM2 / 5224 HGNCID:8889 Length:253 Species:Homo sapiens


Alignment Length:251 Identity:172/251 - (68%)
Similarity:199/251 - (79%) Gaps:1/251 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    42 YRIVMVRHGESEWNQKNLFCGWFDAKLSEKGQQEACAAGKALKDAKIEFDVAHTSVLTRAQETLR 106
            :|:||||||||.|||:|.|||||||:|||||.:||....||:||||:|||:.:||||.||..||.
Human     4 HRLVMVRHGESTWNQENRFCGWFDAELSEKGTEEAKRGAKAIKDAKMEFDICYTSVLKRAIRTLW 68

  Fly   107 AALKSSEHKKIPVCTTWRLNERHYGGLTGLNKAETAKKFGEEKVKIWRRSFDTPPPPMEKDHEYY 171
            |.|..::...:||..|||||||||||||||||||||.|.|||:|||||||||.|||||::.|.||
Human    69 AILDGTDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDIPPPPMDEKHPYY 133

  Fly   172 ACIVEDPRYKDQLKPEEFPKSESLKLTIERTLPYWNEVIVPQIKDGMRVLIAAHGNSLRGVVKHL 236
            ..|.::.||.. |||.|.|..||||.||.|.||:|||.||||||.|.|||||||||||||:||||
Human   134 NSISKERRYAG-LKPGELPTCESLKDTIARALPFWNEEIVPQIKAGKRVLIAAHGNSLRGIVKHL 197

  Fly   237 ECISDKDIMSLNLPTGIPFVYELDESLKPLATLKFLGDPETVKKAMESVANQGKAK 292
            |.:||:.||.||||||||.||||::.|||...::||||.|||:||||:||.|||||
Human   198 EGMSDQAIMELNLPTGIPIVYELNKELKPTKPMQFLGDEETVRKAMEAVAAQGKAK 253

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
Pglym87NP_652041.2 gpmA 42..292 CDD:184516 170/249 (68%)
PGAM2NP_000281.2 pgm_1 4..251 CDD:213596 168/247 (68%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:P00950 10..17 5/6 (83%)