Protein Alignment fbl and Pank1

DIOPT Version :10

• Sequence 1: NP_524870.1
• Gene: fbl / 46234
• FlyBaseID: FBgn0011205
• Length: 512
• Species: Drosophila melanogaster
• Sequence 2: NP_001107811.1
• Gene: Pank1 / 75735
• MGIID: 1922985
• Length: 548
• Species: Mus musculus
• Alignment Length: 466
• Identity: 252/466 - (54%)
• Similarity: 312/466 - (66%)
• Gaps: 42/466 - (9%)

  Fly    27 SPSPPTSPVISAKRNSWRASWRSALGSKSKSIAMA--------------SDSSSD--------PI 69
            |.||.|:|.:....:......|:||.|.......|              :.||.|        |.
Mouse    88 SRSPRTAPPVPGMGDRGAQHERAALQSPGAPEGAAAAVNGLLHNGFHPSAASSRDPPAPRFQLPS 152

  Fly    70 DLEAEPVFFEH----SRCNSYCSSSSAFTELPHPAIQIPQGDELMSMPWFGMDIGGTLTKLVYFE 130
            :|:.:|:|.:|    .:|.......|.....|             ..|||||||||||.||||||
Mouse   153 ELQPQPLFAQHDSPAKKCRLRRRMDSGRKNRP-------------PFPWFGMDIGGTLVKLVYFE 204

  Fly   131 PKDITPDEQDREAGILRNIRRYLTKNSAYGKTGHRDTHLQMDNVEIRKRRGSLHFIRFQTTDMGN 195
            |||||.:|:..|...|::||:|||.|:||||||.||.||::.|:.:..|:|:||||||.|..|..
Mouse   205 PKDITAEEEQEEVENLKSIRKYLTSNTAYGKTGIRDVHLELKNLTMCGRKGNLHFIRFPTCAMHL 269

  Fly   196 FLSLAKQKGMAELVTTVCATGGGAFKFEQDFRDQVNMKLAKFDELDTLIKGILFAD---LHNRTE 257
            |:.:..:|..:.|.||:|||||||||||:|||...:::|.|.||||.||:|:|:.|   .:.:.|
Mouse   270 FIQMGSEKNFSSLHTTLCATGGGAFKFEEDFRMIADLQLHKLDELDCLIQGLLYVDSVGFNGKPE 334

  Fly   258 CYYYENARDILKSEKQQFNFSQPFPFILVNVGSGVSILAVYGPDNYKRISGTSLGGGTFLGLCCL 322
            |||:||..:....:|:.:....|:|.:|||:||||||||||..|||||::|||||||||||||||
Mouse   335 CYYFENPTNPELCQKKPYCLDNPYPMLLVNMGSGVSILAVYSKDNYKRVTGTSLGGGTFLGLCCL 399

  Fly   323 LTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDLVASSFGQMHLNDKRVSVSREDL 387
            ||||.:||||:.:|.|||:..|||||||||||||.||||.|..||||||.|...:||.|:|:|||
Mouse   400 LTGCETFEEALDMAAKGDSTNVDKLVKDIYGGDYERFGLQGSAVASSFGNMMSKEKRESISKEDL 464

  Fly   388 ANATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMKLLAYAMEFWSNGTMKGLFLEHE 452
            |.|||||||||||||||||||||.||||||||||||:|.:|||||||||:|||.|.:|.||||||
Mouse   465 ARATLVTITNNIGSIARMCALNENIDRVVFVGNFLRINMVSMKLLAYAMDFWSKGQLKALFLEHE 529

  Fly   453 GYFGALGCLLQ 463
            |||||:|.||:
Mouse   530 GYFGAVGALLE 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fbl	NP_524870.1	ASKHA_NBD_PanK-II_Pank1-like	114..462	CDD:466972	228/350 (65%)
Pank1	NP_001107811.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..120		9/31 (29%)
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:23152917	1..8
		PHA03309	<5..>185	CDD:165564	21/109 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..167		8/34 (24%)
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:23152917	168..185		3/29 (10%)
		ASKHA_NBD_PanK-II_Pank1	188..539	CDD:466985	228/350 (65%)