DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fbl and pank4

DIOPT Version :9

Sequence 1:	NP_524870.1	Gene:	fbl / 46234	FlyBaseID:	FBgn0011205	Length:	512	Species:	Drosophila melanogaster
Sequence 2:	NP_001120490.2	Gene:	pank4 / 100145609	XenbaseID:	XB-GENE-1012421	Length:	769	Species:	Xenopus tropicalis

Alignment Length:	358	Identity:	136/358 - (37%)
Similarity:	201/358 - (56%)	Gaps:	38/358 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 FGMDIGGTLTKLVYFEPKDITPDEQDREAGILRNIRRYLTKNSAYGKTGHRDTHLQMDNVEIRKR 179
            |.:||||:||||.|:.                 .::..:.|..::..||....|.|:..:.:::.
Frog    35 FAIDIGGSLTKLAYYS-----------------TVQHKVAKVRSFDHTGKDADHEQLYEISVQEE 82

  Fly   180 -RGSLHFIRFQTTDMGNFLSLAKQKGMAELVTT----VCATGGGAFKFEQDFRDQVNMKLAKFDE 239
             ...||||:|:...:...|...|.    .||.|    :.||||||:||:.....::.:|:.|.||
Frog    83 ITARLHFIKFENAYIEICLDFIKD----HLVNTETKVIKATGGGAYKFKDLIEKKLGLKVDKEDE 143

  Fly   240 LDTLIKGILFADLHNRTECYYYENARDILKSEKQQFNF--SQP--FPFILVNVGSGVSILAVYGP 300
            :..||||..|...:...|.:.|      :|....:|.|  :.|  ||::|||:||||||:.|...
Frog   144 MTCLIKGCNFVLKNIPHEAFVY------VKHADPEFRFQTTHPNIFPYLLVNIGSGVSIVKVEAE 202

  Fly   301 DNYKRISGTSLGGGTFLGLCCLLTGCTSFEEAIQLATKGDNRKVDKLVKDIYGGDYNRFGLPGDL 365
            |.::||.|:|:|||||.||..|||....|:|.:|||.||.:..||.||||||||.|...||.|:|
Frog   203 DKFERIGGSSIGGGTFWGLGALLTKTKRFDELLQLAAKGHHTNVDMLVKDIYGGAYQILGLTGNL 267

  Fly   366 VASSFGQMHLNDKRVSVSREDLANATLVTITNNIGSIARMCALNEKIDRVVFVGNFLRVNPISMK 430
            :|||||:....||  ..|:||:|.:.|..|:|:||.:|.:.|....:.:|.|.|.|:|.:|::|.
Frog   268 IASSFGKSATIDK--DFSKEDMAKSLLHMISNDIGQLACLYAKQHNLSQVYFGGFFIRGHPVTMH 330

  Fly   431 LLAYAMEFWSNGTMKGLFLEHEGYFGALGCLLQ 463
            .::|::.|:|.|.::.|||.||||.|.:|..|:
Frog   331 TISYSINFFSKGEVQALFLRHEGYLGTIGAFLK 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fbl	NP_524870.1	Fumble	115..460	CDD:281610	134/353 (38%)
pank4	NP_001120490.2	PLN02902	15..769	CDD:215489	136/358 (38%)
		Fumble	35..360	CDD:281610	134/353 (38%)
		DUF89	447..760	CDD:280170
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D865329at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920