DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)07882 and Nop14

DIOPT Version :9

Sequence 1:	NP_001303435.1	Gene:	l(3)07882 / 46201	FlyBaseID:	FBgn0010926	Length:	852	Species:	Drosophila melanogaster
Sequence 2:	NP_001381523.1	Gene:	Nop14 / 289724	RGDID:	1305605	Length:	862	Species:	Rattus norvegicus

Alignment Length:	868	Identity:	299/868 - (34%)
Similarity:	479/868 - (55%)	Gaps:	89/868 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 NPFDVHVNKEKFKILGRICKHDRGMPGVSRAKALQKRAQTLGQQFAVKHKTNRFKDNRIGKHLSG 101
            |||:|.||::||:||||..:||.|:||||||:|::||.|||.:::..::|:|.|.|.|.|::.|.
  Rat    30 NPFEVKVNRQKFQILGRKTRHDVGLPGVSRARAIKKRTQTLLKEYKERNKSNVFTDKRFGEYNSN 94

  Fly   102 DQLTESVMNARYLAEKMSQVRSNQKAEKFNLNDDELLTHRGQTLEEIEQYRDERSDDEELDDE-A 165
            ....|.:|. |:..|   |.|.::|...:|||:||.|||.||:|.:||::.|....|.:.:|. |
  Rat    95 ISPEEKMMK-RFALE---QQRYHEKKNIYNLNEDEELTHYGQSLADIEKHNDIVDSDSDTEDRGA 155

  Fly   166 LDADFTAAAHFGG------------EGDSAQDRQAAIDEMIVEQKRRKNEIAKEKDEVYDLTEKL 218
            |.|:.| |:||||            :||..:.|:..|:|:|.:.|:.|.|...::::..:|||||
  Rat   156 LSAELT-ASHFGGGVHKNSSQKEGEDGDKPKTRKELIEELIAKSKQEKRERQAQREDALELTEKL 219

  Fly   219 DANYKLLLPLVAKVTK----DEQDAKPPPDAYDKLLKEMIFEPRGSVADKLINPDELAKQEAARL 279
            |.::|.:..|:::.:|    .|:..||.|||||.:::|:.||.:...::::...:||||:|..:|
  Rat   220 DQDWKEIQILLSRKSKKSENKEKKEKPQPDAYDMMVRELGFEMKAQPSNRMKTEEELAKEEQEKL 284

  Fly   280 EKLENERLRRMRADGEEDEEASVAKPKHRSADDLDDGYFLAGEDDEGDDTLAYDLDGNLGTHLNG 344
            .|||.||||||..   :||..:..||||.|||||:||:.|    |:.|..|....||.:  ::..
  Rat   285 RKLEAERLRRMLG---KDEHENKKKPKHTSADDLNDGFIL----DKDDRRLLSYKDGKM--NIED 340

  Fly   345 KKEAVLKGDENEDDDDKEGEEEEEEDSD--------EESDSEVDNLSDLKESESESEPEEAPKAS 401
            .:|...||.:.:::|.||.|:|.||:.:        :|||.. |:.|||:.|....|.:|.||..
  Rat   341 AQEEQSKGADGQENDQKEEEDESEEEGEDGESCEDPDESDGP-DSHSDLESSAETEEEDETPKKE 404

  Fly   402 KK-----KAKKSADTIPASLDTSIPFTIKMPKTYEDFTELLSKHATAQKAIIIERIIKCNHPKLE 461
            ::     |:.|.|.....:....:|:....|:::|:...|||..:..::.:::|||.|||||.|.
  Rat   405 QRQTPGGKSPKEAQKAQKAAAAELPYVFAAPESFEELKFLLSGRSMEEQLLVVERIQKCNHPSLA 469

  Fly   462 GVNRENVVKLYSFLLQYLKDLFEDASEQDIREHFQLLSKLMPYLYELTQLNPERMSNTLLEVIKE 526
            ..|:..:.||:.|||||:.||..| |..|::    .:.||:.:||.|.|:.||..|:.:..|:::
  Rat   470 VGNKAKLEKLFGFLLQYIGDLATD-STPDLK----TIDKLVVHLYNLCQMFPESASDAIRFVLRD 529

  Fly   527 KYEEFR-----KNHKMYPSLDTLVYFKLVANLYSTSDFRHPVVTPCFIFIQHVLSRSRVRTRQEI 586
            ...|..     |....:|.||.|:|.|:...|:.||||.||||||..|.:..:|::..|.:.:::
  Rat   530 AMHEMEEMIETKGRAAFPGLDVLIYLKITGLLFPTSDFWHPVVTPALICMSQMLTKCPVTSLRDV 594

  Fly   587 SMGLFLVTVVLEFVSQSKRLVPAVFNFLQGIVHMSIPKRDVEQLEITPPFERDGPLSKLL----- 646
            ..|||:..:.||:||.|:|.||.:.|||.||::::.|.:..:...:..||...|..|:||
  Rat   595 VKGLFVCCLFLEYVSLSRRFVPELLNFLLGILYIATPNKKSQGSTLVHPFRALGKNSELLVVSDK 659

  Fly   647 ---------ALP---ANTESTKLEPQQLQPTDLVTQTITPDFKVRALDTSLLLIKEALQLVEEHV 699
                     :||   ||.:||            :|.|.....::..:.:.|.|:|..:.:.....
  Rat   660 ADVTTWQRGSLPLHWANRQST------------LTATEANHTRLSCVASCLSLLKHCVLMYSALP 712

  Fly   700 GACYLAQPFLALLSRLPLESYPEHVHQHHKDATELAEKLAAQKM--KPLAPAEKKPKALRLLEPR 762
            ....:..|..|||:.....|.|:.:.:..:   .:..::.:||.  .||...:.||..|:...||
  Rat   713 SFHAIVTPHQALLAEHLARSLPQELQELSR---SILSEVESQKQHCPPLICEKSKPVPLKQFTPR 774

  Fly   763 FEAVYDDKRRPKMSKAKEERAKLLHKIKREKKGAIREIRRDTSFVQMLRLKQTLQSDKERHEKVK 827
            ...|.:..|:...||.::||.:|:||.|||.|||:||||:|..|:..::|.:.::.|.||..|||
  Rat   775 LVKVLEFGRKQGSSKEEQERKRLIHKHKREFKGAVREIRKDNQFLARMQLSEIMERDAERKRKVK 839

  Fly   828 RIYQEASVQQGELNELSRAKKKK 850
            :::...:.|:||...|.|.|.||
  Rat   840 QLFNSLATQEGEWKALKRKKFKK 862

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)07882	NP_001303435.1	Nop14	30..839	CDD:282059	292/855 (34%)
Nop14	NP_001381523.1	Nop14	26..851	CDD:398014	292/855 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335616
Domainoid	1	1.000	469	1.000	Domainoid score	I438
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41773
Inparanoid	1	1.050	476	1.000	Inparanoid score	I1429
OMA	1	1.010	-	-		QHG55312
OrthoDB	1	1.010	-	-		D288485at33208
OrthoFinder	1	1.000	-	-		FOG0004332
OrthoInspector	1	1.000	-	-		oto97449
orthoMCL	1	0.900	-	-		OOG6_103518
Panther	1	1.100	-	-	LDO	PTHR23183
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5420
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910