Protein Alignment SERPINC1 and Spn28F

DIOPT Version :9

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_524957.2
• Gene: Spn28F / 49807
• FlyBaseID: FBgn0028987
• Length: 375
• Species: Drosophila melanogaster
• Alignment Length: 427
• Identity: 121/427 - (28%)
• Similarity: 209/427 - (48%)
• Gaps: 72/427 - (16%)

Human    84 SKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTS 148
            :..:.|||..|||.|| .:|..:|:..||||:..|.:|..:||...|.|::..|.|.....::.:
  Fly    11 TSVSCRFADDFYQLLA-KENAANNLISSPLSVEIALSMAYMGARAKTAQEMRNVLKLPDDKKEVA 74

Human   149 DQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQ 213
            .:.....:||..|     .|.:.|..|||::.:|......:|..:.:..:.|:.:.:|..: ..:
  Fly    75 AKYKDLLSKLEGR-----EKVATLSLANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIVD-PNK 133

Human   214 SRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFK 278
            :.:.:|.||.|:|.|:|.|::.|..::::.::|| |.||||
  Fly   134 ASSIVNNWVDNQTRGKIKDLVSSNDMSKMELIVL-NAIYFK------------------------ 173

Human   279 WRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQV 342
                             |.|:.||:|:.|:|..|..:|.:|....||.....||....:| |.::
  Fly   174 -----------------GQWEYKFNPKLTKKRNFRVSDQKSVPVEMMSLFQSFRAAHDSELGAKI 221

Human   343 LELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQ 407
            :|||::...::|::.||.....|:::||::.     .:..:|.:|.:.:.:|:|:||....|.:.
  Fly   222 IELPYRNSSLSMLIFLPDQVDGLSELEKKIV-----GFKPKLSKMDVTLRLPKFKIEFFAQLNKV 281

Human   408 LQDMGLVDLFSPEKSKLPGIVAEGRD-----DLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRS 467
            |..||:.|.|  |||      |:.:|     :::|....||||:||||||:||||:||::....|
  Fly   282 LVAMGIQDAF--EKS------ADFKDLVENSNVHVKKVIHKAFIEVNEEGAEAAAATALLFVRYS 338

Human   468 --LNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 502
              :..:::.|.|:.||...||:  ..||.|.|....|
  Fly   339 MPMPSSQMVFNADHPFAYVIRD--RETIYFQGHFVKP 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	121/427 (28%)
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	120/419 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	9	8.940