Protein Alignment SERPINC1 and Spn38F

DIOPT Version :10

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_524956.2
• Gene: Spn38F / 49806
• FlyBaseID: FBgn0028986
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 428
• Identity: 125/428 - (29%)
• Similarity: 200/428 - (46%)
• Gaps: 77/428 - (17%)

Human    84 SKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTS 148
            :..:.||....||.|| .:|.:.|:..||||:..|.::..:||...|.|::.:|.|.....::.:
  Fly    11 TSVSCRFTDDLYQLLA-KENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKKEVA 74

Human   149 DQIHFFFAKLNCRLYRKANKSSKLVS-ANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAE 212
            .:.....:||..|      :|..::| |||::.:........|..:.:..:.|:.:.:. ..|.:
  Fly    75 AKFKDLLSKLEGR------ESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAIS-ANNPK 132

Human   213 QSRAAINKWVSNKTEGRITD-VIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFF 276
            .:.:.:||||..:|.|:|.| |:||:..|  .|||::|.||||
  Fly   133 ITASIVNKWVDTQTSGKIRDLVMPSDVAN--LVLVILNAIYFK---------------------- 173

Human   277 FKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKF--RYRRVAEG 339
                               |.|:.||:.|.|:.: |:.:|.:|....||.....|  .|.|.. |
  Fly   174 -------------------GQWQKKFNTEQTKSD-FHISDQKSVPVQMMSLVRPFGVSYDREL-G 217

Human   340 TQVLELPFKGDDITMVLILPKPEKSLAKVEKEL---TPEVLQEWLDELEEMMLVVH--MPRFRIE 399
            ..|:|||::..:::||:.||.....|.::||::   ||:::.          :.||  :|:|:||
  Fly   218 ANVIELPYRNSNLSMVIFLPDKVDGLPELEKKMVGFTPKLIN----------INVHLRLPKFKIE 272

Human   400 DGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIA 464
            ....|::.|..||:.|.|. ..:....:||  ....:|....||||||||||||||||:||||..
  Fly   273 FSARLEQVLIAMGIQDAFK-TSADFNDLVA--NSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFR 334

Human   465 GRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 502
            .:|:....:.|..|.||...||:.  ..|.|.|...||
  Fly   335 YKSIRSPPMDFNVNHPFAYVIRDA--ENIYFQGHFVNP 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	125/428 (29%)
Spn38F	NP_524956.2	serpin42Dd-like_insects	12..370	CDD:381070	123/425 (29%)