Protein Alignment SERPINC1 and Spn42Da

DIOPT Version :10

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_524955.2
• Gene: Spn42Da / 49805
• FlyBaseID: FBgn0265137
• Length: 424
• Species: Drosophila melanogaster
• Alignment Length: 428
• Identity: 125/428 - (29%)
• Similarity: 203/428 - (47%)
• Gaps: 69/428 - (16%)

Human    82 ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEK 146
            |.::..:.|:...|..|:..| ..:||..||.||.|..||.:|||.|:|..||.:..   .::..
  Fly    40 EFARRLALFSINVYGKLSGQK-PGENIVFSPFSIQTCAAMARLGAENETATQLDQGL---GLASS 100

Human   147 TSDQI-HFFFAKLNCRLYRKANKSSKLVS-ANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKE 209
            ..:|| |.|...|      .|.:.|:::. ||::|........:.:..:....:.:..|.:||.:
  Fly   101 DPEQIAHSFHQVL------AAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSK 159

Human   210 NAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTP 274
            |. |:.|.||.||..:|...|.|::|::.:|..:.|||||.|:||
  Fly   160 NV-QAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFK-------------------- 203

Human   275 FFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGE-SCSASMMYQEGKFRYRRV-A 337
                                 |.|:.:|:...||.:.|: .||| :....||..:.:|||..: |
  Fly   204 ---------------------GTWQHQFAKHLTRPDTFH-LDGERTVQVPMMSLKERFRYADLPA 246

Human   338 EGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGF 402
            .....||||:|..|::|:::||..:..|..:|::|....|.:....|.|..:.:.:|||:.|...
  Fly   247 LDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKLRLTTLSQITQSLYETKVALKLPRFKAEFQV 311

Human   403 SLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRS 467
            .|.|..|.:|:..:||.:...  |.:.:..:.|.||...||||:||||||:||||:|.:.:..:.
  Fly   312 ELSEVFQKLGMSRMFSDQAEF--GKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKR 374

Human   468 --LNPNR-VTFKANRPF---LVFIREVPLNTIIFMGRV 499
              ::|.. :.|.|:.||   ||..:::||    |.|.|
  Fly   375 AIMSPEEPIEFFADHPFTYVLVHQKDLPL----FWGSV 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	125/428 (29%)
Spn42Da	NP_524955.2	serpin42Da-like	45..407	CDD:381065	122/420 (29%)