Protein Alignment SERPINC1 and Spn27A

DIOPT Version :9

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_001260143.1
• Gene: Spn27A / 45815
• FlyBaseID: FBgn0028990
• Length: 447
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 125/513 - (24%)
• Similarity: 226/513 - (44%)
• Gaps: 89/513 - (17%)

Human     8 TVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKI 72
            |...|...|.||||.|...   .|.:|:.:...|        .|..::   |.:..:..|....:
  Fly     2 TKMGGNLAVMLLSLFLSAL---ATGNGNSIPTTT--------TPQGVF---ETRTDKLPGGAASV 52

Human    73 PEATNRRVWE--------LSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACND 129
            |....  :::        .|.::..|:....:.:..::..:.|:.:||.|:....|:....|...
  Fly    53 PSGAG--IYDDIDTFVPFRSDSHDPFSWHLLKTVLQNETADKNVIISPFSVKLVLALLAEAAGAG 115

Human   130 TLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSA-NRLFGDKSLTFNETYQDI 193
            | |..:|:....|.....::...|:...||.  ::|.|:..:.:|. .:||.|   :|.||.|..
  Fly   116 T-QTQVELANTQTDIRSQNNVREFYRKTLNS--FKKENQLHETLSVRTKLFTD---SFIETQQKF 174

Human   194 SELV---YGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKV 255
            :..:   |.::::.||| .|.|.:..|||.|.:|.|:||:..::..:.:.. :|::|.|.|||
  Fly   175 TATLKHFYDSEVEALDF-TNPEAAADAINAWAANITQGRLQQLVAPDNVRS-SVMLLTNLIYF-- 235

Human   256 LRMALERPQGLPLALQLTPFFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESC 320
                                                   .|||:.:|:  .|.:..|:::..:..
  Fly   236 ---------------------------------------NGLWRRQFA--TTFQGSFFRSKDDQS 259

Human   321 SASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQ--EWLD 382
            .|..|.|...|.|....: ..|:|.||:||.: ::.::||.....:..:.|.|..:.|:  :|
  Fly   260 RAEFMEQTDYFYYTTSEKLKAQILRLPYKGKN-SLFVLLPYALNGIHDLVKNLENDELKSAQW-- 321

Human   383 ELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIV--AEGRDDLYVSDAFHKAF 445
            .:||:.:.|.:|:|..:...:|||.|:.:|:.::|. :.:.|||:.  |:....:.||:...||.
  Fly   322 AMEEVKVKVTLPKFHFDYQQNLKETLRSLGVREIFE-DSASLPGLTRGADVAGKVKVSNILQKAG 385

Human   446 LEVNEEGSEAAASTAVVIAGRSLNPNRV-TFKANRPFLVFIREVPLNTIIFMGRVANP 502
            :.|||:|:||.|:|.|.|..:......: .|..||||:.||.|.....|:|.|:|.:|
  Fly   386 INVNEKGTEAYAATVVEIENKFGGSTAIEEFNVNRPFVFFIEEESTGNILFAGKVHSP 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	111/451 (25%)
Spn27A	NP_001260143.1	SERPIN	72..440	CDD:238101	107/422 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.030