Protein Alignment SERPINC1 and Spn43Ab

DIOPT Version :10

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_001027395.1
• Gene: Spn43Ab / 45040
• FlyBaseID: FBgn0024293
• Length: 393
• Species: Drosophila melanogaster
• Alignment Length: 420
• Identity: 92/420 - (21%)
• Similarity: 184/420 - (43%)
• Gaps: 99/420 - (23%)

Human   105 NDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKF-----DTISEKTSDQIHFFFAKLNCRLYR 164
            |:|:.:||.:|.::.|:..:||...|..:|.:..:.     |.:|:::..             |:
  Fly    46 NENVVISPATIQSSMALAFVGAKGQTASELQQGLRLGPGDADAVSQRSGS-------------YQ 97

Human   165 KA-NKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDF-----KENAEQSRAAINKWVS 223
            :| .:.:....||.::.:::|.|..:::|:::..:.:.:..|||     |..|:    .||:.|:
  Fly    98 QALTRDNNFRLANNIYINENLEFKGSFRDVAQRQFDSNIDKLDFHPPYNKRTAD----GINRAVA 158

Human   224 NKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFKWRDRSPERAN 288
            .||.|:|||::.:|.:|:.|..|:||.:.:
  Fly   159 TKTNGKITDILRAELLNDRTEGVIVNGVSY----------------------------------- 188

Human   289 GLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRV-AEGTQVLELPFKGDDI 352
                  ...|:..|..:.|.|..|....|:|.....|:....|.|..| :...:|:|||::..|.
  Fly   189 ------SAAWQKAFRLDKTEKRSFRTGSGQSVKVDTMWTLQNFNYAEVNSLDAKVVELPYQNPDF 247

Human   353 TMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLF 417
            :|:|:||..:..|..:::.|:.:.|...:..:.:..:.|.:|:|.:..|..|:...:.:|:..:|
  Fly   248 SMLLLLPNRKDGLRSLQQSLSGKNLLAEIGAMSQQKVEVLLPKFSVTFGLGLEGPFKKLGVHTMF 312

Human   418 SPEKSKLPGIVAEGRD----DLY-------VSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPN 471
            |             ||    ::|       ::...|||.:||.|.|.:....|.::   :.|...
  Fly   313 S-------------RDGDFGNMYRMFVSHFINAVEHKANVEVTEAGVDQPLETGLL---KGLFSR 361

Human   472 RVTFKANRPFLVFIREVPLNTIIFMGRVAN 501
            ...|:|:.||:..|:.  .::|.|:|.:||
  Fly   362 SKKFEADHPFVFAIKY--KDSIAFIGHIAN 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	92/420 (22%)
Spn43Ab	NP_001027395.1	serpin42Dd-like_insects	27..390	CDD:381070	92/420 (22%)