Protein Alignment SERPINC1 and Spn77Bb

DIOPT Version :9

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_649206.1
• Gene: Spn77Bb / 40235
• FlyBaseID: FBgn0036969
• Length: 362
• Species: Drosophila melanogaster
• Alignment Length: 408
• Identity: 92/408 - (22%)
• Similarity: 148/408 - (36%)
• Gaps: 108/408 - (26%)

Human   125 GACNDTLQQLMEVF----KFDTISEKTSDQIHFFFAKLNCRLYRKAN-KSSKLVSANRLFGDKSL 184
            ||...|:.:|.:|.    .:.|:.....|          .|.|...| :::||.|....:
  Fly    20 GAEGYTVNELRDVLGIYVDYPTLRRWYED----------VRAYHYLNSENTKLFSLRYAY----- 69

Human   185 TFNETYQDIS--ELVYG------------------AKLQPLDFKENAEQSRAAINKWVSNKTEGR 229
                 |.|:.  |||.|                  .:.:.:||.:.|.   ..||..:...:..:
  Fly    70 -----YDDVGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVDFDQGAS---IIINDDIDKASHAK 126

Human   230 ITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFKWRDRSPERANGLPKAT 294
            |.......:.|....::.:...|||
  Fly   127 IFSSYSRRSFNSTVTVLGITVSYFK---------------------------------------- 151

Human   295 QGLWKSKFSPENTRKELFYKADGESC-SASMMYQEGKFRYRRVAEGTQ--VLELPFKGDDITMVL 356
             ..||..|....|:.|.||...|... ...||.|.||:.|....:|.|  ||||||...::.|::
  Fly   152 -AKWKYPFDKSQTKVEQFYNDGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEHELVMIV 215

Human   357 ILPKPEKSLAKVEKELTPEVLQEWLDELE----EMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLF 417
            :|||..:.:..|..:|....|...|::||    |..:.|.:|:|......||::.:.|.||.||.
  Fly   216 LLPKSSQGVNLVLYQLKNLGLHRLLEKLEASKNETDVEVKLPKFDTRSVLSLEDTVYDAGLTDLR 280

Human   418 S--PEKSKLPGIVAEGRDDLYVSDAFHK-AFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANR 479
            :  .:..||  ::|.|.....:: .:|: |.:.|:|||...|      :..:|...|.:.|..||
  Fly   281 NDFADLDKL--LIAIGHRGACLT-LYHQFARIVVDEEGLPNA------VPQKSSGKNNIKFHVNR 336

Human   480 PFLVFIREVPLNTIIFMG 497
            ||...:.:.....:|..|
  Fly   337 PFAYLVLQKKHKLLIHSG 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	92/408 (23%)
Spn77Bb	NP_649206.1	SERPIN	13..356	CDD:238101	92/408 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920