Protein Alignment SERPINC1 and Spn77Ba

DIOPT Version :10

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_649205.3
• Gene: Spn77Ba / 40234
• FlyBaseID: FBgn0262057
• Length: 450
• Species: Drosophila melanogaster
• Alignment Length: 506
• Identity: 115/506 - (22%)
• Similarity: 195/506 - (38%)
• Gaps: 97/506 - (19%)

Human    22 LLIGFWDCVTCHGSPVDICTAKPRD--IPM-----NPMCIYRSPEKKATEDEGSEQKIPEATNR- 78
            ||:|          .:.:|:|.|::  .|:     ||:..:.:|    |..:.....|....:.
  Fly    14 LLLG----------AIFLCSADPQNNQAPLQLSVGNPLTAFTAP----TAFQSGVSHIQSMRSNF 64

Human    79 ---RVWELSKANSRFATTFYQHLA-DSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFK 139
               .:..:|:....||....|.:: :.:..|.:..:||.|:.:...:...|:..:|..||.:..:
  Fly    65 DTDVLVSISQGVQDFALDLLQRISVEVEKANKDFMISPFSVWSLLVLLYEGSEGETRNQLKKSLR 129

Human   140 FDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQP 204
            .:...||.......:.:.||.     ...:.::.:...::..|.......|:|   .:....:||
  Fly   130 INVEDEKLRGAYKVWSSFLNI-----TTSTIEVATLQAIYTGKGYPIKNNYRD---AIQNYNVQP 186

Human   205 LDFKENAEQSRAAINKWVSNKTEGRIT-DVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPL 268
            ::....:..|...||:..:..|.|.|. .::|.:...  ..:.|::::|||
  Fly   187 MEVDFYSPDSVIQINEDTNRTTRGLIPYTILPQDVYG--AKMFLLSSLYFK-------------- 235

Human   269 ALQLTPFFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESC-SASMMYQEGKFR 332
                                       |.||..|:...||:|.|:...||.. ...||.||..|.
  Fly   236 ---------------------------GQWKFPFNKTLTREEPFFSESGEVIGKIPMMVQEANFA 273

Human   333 YRRVAEGTQ--VLELPFKGDD-ITMVLILPKPEKSLAKVEKELTPEVLQEWLDEL--------EE 386
            |....||..  |||||:...| :.|:::|||....|..|...|....|:..|..|        |:
  Fly   274 YVSNVEGLDGYVLELPYGTQDRLAMIVVLPKRGFKLNDVANNLKALGLRPILQRLAAFRNRASED 338

Human   387 MMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEE 451
            ..:.|.||:|.....|:||..|..||:.|||....:.|..:    ...|:.....|...:.|:|:
  Fly   339 NEVEVMMPKFVTATDFTLKGVLIQMGIRDLFDENTANLDRM----SSGLFAKLVVHSTKIIVDEQ 399

Human   452 GSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 502
            |:.|.|.|...:|.::..|.   |..||||...|.|.....::|.|:|.||
  Fly   400 GTTAGAVTEAALANKATPPK---FLLNRPFQYMIVEKATGLLLFAGQVRNP 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	104/451 (23%)
Spn77Ba	NP_649205.3	serpin77Ba-like_insects	72..447	CDD:381062	101/432 (23%)