Protein Alignment SERPINC1 and Spn53F

DIOPT Version :9

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_001036553.1
• Gene: Spn53F / 36931
• FlyBaseID: FBgn0034195
• Length: 379
• Species: Drosophila melanogaster
• Alignment Length: 459
• Identity: 91/459 - (19%)
• Similarity: 158/459 - (34%)
• Gaps: 137/459 - (29%)

Human    84 SKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQL-------------- 134
            ::.||:.....|..:.:|.: |.||..|...|.::.....:|...|..:|:
  Fly    16 AQKNSQLPDELYAAIVNSFS-NRNIMFSTEMIRSSMLFIYVGVEEDESEQIRKAMHYRGTHLSEY 79

Human   135 ----MEVFKFDTISEKTSDQIHFFFAKLNCRL---YRKANKSSKLVSANRLFGDKSL----TF-- 186
                .::|.........:..:..|:.:.|.::   ||...:.::..:.|..|..:.|    ||
  Fly    80 KPKTQKIFAMSVKKAPVAKSLTRFYVRQNMKMSTEYRVFMRHTEGRARNIAFAREQLDEVNTFYS 144

Human   187 NETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTI 251
            :|..:.|.::|          ||:          |....::|                 :|||.|
  Fly   145 HEMGEQIGQVV----------KES----------WWKPNSQG-----------------LLVNAI 172

Human   252 YFKVLRMALERPQGLPLALQLTPFFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKAD 316
            :|.:                                         .|:..|:||.|....|....
  Fly   173 FFNL-----------------------------------------SWERTFNPEATYPREFRVNA 196

Human   317 GESCSASMMYQEGKFRYRRVA--EGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQE 379
            .:|....||:::.||.:..:.  :.|.|| :||...|:.|:||.|.....||.::.:|....:..
  Fly   197 TKSVMIPMMHEDSKFAFGILGNLKATAVL-VPFSHGDLRMLLIKPDQPDGLAALQMKLQAMNILS 260

Human   380 WLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKS-----------KLPGIVAEGRD 433
            ....|..|.:.|.:|:|:|.....|....:.||:.|:|.|.||           ::.|::
  Fly   261 VARNLTMMDVFVGIPKFKIHSDLELSPAFEKMGIKDIFKPSKSFSTLLHRNTNFRIDGVI----- 320

Human   434 DLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVT-FKANRPFLVFIREVPLNTIIFMG 497
                    |....|..|:|. ...||.|.....:...|.|. |.|..||..:|  :...:|.|.|
  Fly   321 --------HVVTFEFQEQGI-GTPSTDVGNGSLTHTFNGVKYFLATHPFAFYI--IDNTSIYFAG 374

Human   498 RVAN 501
            .|.:
  Fly   375 HVTS 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	91/459 (20%)
Spn53F	NP_001036553.1	SERPIN	25..376	CDD:238101	88/446 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.030