Protein Alignment SERPINC1 and Spn42De

DIOPT Version :10

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_610246.3
• Gene: Spn42De / 35602
• FlyBaseID: FBgn0033115
• Length: 404
• Species: Drosophila melanogaster
• Alignment Length: 424
• Identity: 127/424 - (29%)
• Similarity: 203/424 - (47%)
• Gaps: 65/424 - (15%)

Human    88 SRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQL-----MEVFKFDTISEKT 147
            ::||:..:..||.|::.. ||..||.||.|..|:..|||...|..:|     :|......::||.
  Fly    33 AQFASQLFGQLAKSQSGR-NIVFSPSSIRTGLALAYLGAEGSTADELKLGLGLEGAGKTEVAEKL 96

Human   148 SDQIHFFFAKLNCRLYRKANKSS---KLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKE 209
             ||:   .||   ..:.||:...   ||..|||:|..:.....:||||:....:.|..:.::|.:
  Fly    97 -DQL---LAK---GQWEKASGDEDVPKLKYANRIFVTQRFKLTQTYQDLVSKNFAAAAENVNFTQ 154

Human   210 NAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTP 274
            .|:.:: .||.||..:|..:|.|:|..|:::..|..:|||.||||.
  Fly   155 KADTAK-HINSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKA------------------- 199

Human   275 FFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE- 338
                  |                |:|.|....|....|....|...|...|.||..||:..:.|
  Fly   200 ------D----------------WQSSFPDYATYASDFVNHGGRKVSVDTMSQEDYFRFGELTEL 242

Human   339 GTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFS 403
            ..:|:|||:.|.||..::|||:.|:.||.||::|....|.|...:|....:.|.:|:|:.|....
  Fly   243 KAKVVELPYTGTDIVFLIILPQEEQGLAIVEEKLMGIDLNEISSQLRRRKVRVQLPKFKFEFDVP 307

Human   404 LKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSL 468
            |:..|:::|:..|||| .:.|..:. :|.:.|.:|:..|||.:||||:|:.|:.:|.:.::..||
  Fly   308 LQAALEELGIKKLFSP-GANLSSLY-QGSEPLRISEVKHKAIIEVNEKGTTASGATFIKVSVESL 370

Human   469 NPNRVTFK--ANRPFLVFIREVPLNTIIFMGRVA 500
            ......|:  |:.||...|::.. || :|:|.|:
  Fly   371 TIGEEVFEFIADHPFFFAIKDAQ-NT-LFLGHVS 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	127/424 (30%)
Spn42De	NP_610246.3	serpin42Dd-like_insects	30..403	CDD:381070	127/424 (30%)