Protein Alignment SERPINC1 and Spn42Dc

DIOPT Version :10

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_610245.2
• Gene: Spn42Dc / 35600
• FlyBaseID: FBgn0033113
• Length: 403
• Species: Drosophila melanogaster
• Alignment Length: 411
• Identity: 112/411 - (27%)
• Similarity: 192/411 - (46%)
• Gaps: 60/411 - (14%)

Human    98 LADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFF-----FAK 157
            |..||:.:.|...||.|:.:|..:..:||...|.::|....:..     ..|:.|..     |.:
  Fly    24 LQQSKDPHINTVFSPASVQSALTLAFMGASGSTAEELRNGLQLG-----PGDRHHIALNFGEFWR 83

Human   158 LNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWV 222
            .:|..   .::...|.|.|||:.:.||.....:.:|:...:.:|.:...|.: :|.:...||.||
  Fly    84 TSCNY---GDRGPVLKSVNRLYVNDSLELLTEFNEIAVDFFQSKAEATRFAD-SEGATQLINDWV 144

Human   223 SNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFKWRDRSPERA 287
            ..:||.:||:::.|:|:|..|..:|:|.:|||
  Fly   145 EQETEHKITNLLQSDAVNNETSALLINVLYFK--------------------------------- 176

Human   288 NGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDD 351
                    |.|:..|.||.|..:.|:.........:|||||.|||:..:.: ..:.::||:...:
  Fly   177 --------GKWQKPFMPETTSIDHFHVDRDTHVQVNMMYQEDKFRFAELPQLKARAVQLPYDYSN 233

Human   352 ITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDL 416
            |.|:::||.....|.::|::|....|.:....|....:.:.:||..||....||:.|..:|:.::
  Fly   234 IHMLILLPNEVNGLQELEQQLNTVDLADIDAALTLQDVEIFLPRMCIEYDVDLKQVLNQLGITEV 298

Human   417 FSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPF 481
            || :|:||.|:.. .:....:|.|.|:.:::|||.||||||.:.:.|....||.|:..|||:.||
  Fly   299 FS-DKAKLDGLFT-SQSGQKISAARHRGYIDVNEAGSEAAAVSFMKIVPMMLNMNKKLFKADHPF 361

Human   482 LVFIREVPLNTIIFMGRVANP 502
            :.:||..  ..:.|.||.:||
  Fly   362 VFYIRNP--QAVFFAGRFSNP 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	112/411 (27%)
Spn42Dc	NP_610245.2	serpin42Dd-like_insects	7..380	CDD:381070	110/409 (27%)