Protein Alignment SERPINC1 and Spn42Db

DIOPT Version :10

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_610244.2
• Gene: Spn42Db / 35599
• FlyBaseID: FBgn0033112
• Length: 388
• Species: Drosophila melanogaster
• Alignment Length: 426
• Identity: 117/426 - (27%)
• Similarity: 198/426 - (46%)
• Gaps: 69/426 - (16%)

Human    82 ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGAC--NDTLQQLMEVFKFDTIS 144
            |.::...:||...:.||..: :...||..|||||..:.||.::|..  :.|.:::.|..:|..:.
  Fly     5 EFAQGLEQFALCLHDHLCRA-SAGLNIIYSPLSIHISAAMLRMGTSEGSATAKEMDEGLRFGGLE 68

Human   145 EKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKE 209
               :.|:...|..    :.:...:...|..||.|:..|.|..:|.:..|.|..:.:|...:||
  Fly    69 ---AQQVAESFGV----VLKSYEQCQVLKMANGLYVMKGLQVDEQFGHILEQKFRSKPMEIDF-- 124

Human   210 NAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTP 274
            .:||:.:.|||||.::|...|.|:|....:.:.:.|.|||.|:||
  Fly   125 GSEQAASIINKWVESQTNNLIKDIIGPRVLTKDSRLCLVNGIHFK-------------------- 169

Human   275 FFFKWRDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMY--QEGKFRYRRVA 337
                                 |.|...|:.:.||:|.|:.:| ......||:  :...|....:.
  Fly   170 ---------------------GEWSISFNEKETREEDFFGSD-RPTRVRMMHVCENFFFAVLPMF 212

Human   338 EGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGF 402
            |.| .|.:.:...::.|:::||..:.:|..:||:|:...|:.....:....:.|.:|.|..|...
  Fly   213 EAT-ALRMNYSACNLAMIILLPDEKSNLTSLEKKLSDISLEVVSSAMNLEKVDVKIPSFTAEFQQ 276

Human   403 SLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRS 467
            .|.:.|..||:..:||.: ::|.|:: :..:.|:||...||||:|:||.|:||||:||.|...||
  Fly   277 ELSQVLMLMGMNRIFSGQ-AELGGML-QSEESLFVSQIVHKAFIEINEVGTEAAAATAAVATFRS 339

Human   468 L----NPNRVTFKANRPFLVFIREVPLNT--IIFMG 497
            :    .|.:| |.|||||...|::   ||  ::|.|
  Fly   340 MPARQGPPKV-FHANRPFFYAIKD---NTHGLLFAG 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	117/426 (27%)
Spn42Db	NP_610244.2	serpin42Da-like	9..372	CDD:381065	116/422 (27%)