Protein Alignment SERPINC1 and Spn28Da

DIOPT Version :9

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_001036345.1
• Gene: Spn28Da / 34082
• FlyBaseID: FBgn0051902
• Length: 384
• Species: Drosophila melanogaster
• Alignment Length: 424
• Identity: 120/424 - (28%)
• Similarity: 199/424 - (46%)
• Gaps: 71/424 - (16%)

Human    89 RFATTFYQ-HLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIH 152
            :|....|: .|.|:|  ..||..|||.:....:|..:||..:|..:|......    .:....:.
  Fly    16 QFTKQLYRSFLQDNK--QYNIIASPLCVEIGMSMILMGADGNTANELRTALNL----PEDKKNVA 74

Human   153 FFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRA- 216
            ..:.||..:|.| ..|.:.|..|||||.::::..|:.|..:....:.|:.:.:..   |::.:|
  Fly    75 TIYDKLLTKLER-GKKVAILHLANRLFVNETIGVNKRYNKLVNKHFRAEAEAIKL---ADRLKAA 135

Human   217 -AINKWVSNKTEGRITD-VIPSEAINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFKW 279
             |||.||.::|...:.| :|||:...:.:. |::|..:||
  Fly   136 WAINDWVLDQTLDNVKDIIIPSDLTPDESA-VMINAAFFK------------------------- 174

Human   280 RDRSPERANGLPKATQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLE 344
                            |.||::|...||:.::||.:.....:.:||.|.|:|: .|.:...|::|
  Fly   175 ----------------GYWKTRFDKMNTKPKVFYVSKSYQVNVNMMSQVGRFK-MRTSTIDQIIE 222

Human   345 LPFKGDDITMVLILPKPEKSLAKVEK--ELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQ 407
            |||...:::||::|||...||.:.|.  |..|:::      |.||.:.|.:|:|:|:....|.|.
  Fly   223 LPFAYSNLSMVIVLPKDNGSLTQAEATIESYPQIV------LTEMDVHVQLPKFKIDFRMELVET 281

Human   408 LQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRS-LNPN 471
            |:.||:.|||:   |.....|...:....:|...||||:|::|||..|.:::|..|.|.| ...:
  Fly   282 LKSMGIQDLFN---SSSDISVLLNQSGTRISQVVHKAFIEIDEEGGSAGSASASPIRGLSDYATS 343

Human   472 RVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK 505
            .|||..|.||:..||:.  :.|.|.|||.:|..|
  Fly   344 VVTFTVNSPFVFMIRDD--DNIYFRGRVVDPLKK 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	119/421 (28%)
Spn28Da	NP_001036345.1	SERPIN	16..369	CDD:238101	116/416 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.980