Protein Alignment SERPINC1 and Spn28Db

DIOPT Version :9

• Sequence 1: NP_001373231.1
• Gene: SERPINC1 / 462
• HGNCID: 775
• Length: 505
• Species: Homo sapiens
• Sequence 2: NP_001356884.1
• Gene: Spn28Db / 326261
• FlyBaseID: FBgn0053121
• Length: 377
• Species: Drosophila melanogaster
• Alignment Length: 401
• Identity: 101/401 - (25%)
• Similarity: 173/401 - (43%)
• Gaps: 78/401 - (19%)

Human   107 NIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDT-ISEKTSDQIHFFFAKLNCRLYRKANKSS 170
            |...|||.|....:|..:||...|.::|..|..... ::|         .||...|:.....|.:
  Fly    38 NFIASPLCIEIGISMILMGAKGTTAEELRSVLDLPVDVTE---------MAKKYERIMSNFQKHN 93

Human   171 KLVSANRLFGDKSLTFNETY---QDISELVYGAKLQPLDFKENAEQSRA--AINKWVSNKTEGRI 230
            .|...|.|:      .||||   ||.:.|:....:  .:.|:...|.:|  :|:..:..|:...:
  Fly    94 GLRFTNWLY------VNETYEVRQDYNTLMKSTFM--AEGKDPLSQRKASNSISFSIHRKSHKGM 150

Human   231 TDVIPSE--AINELTVLVLVNTIYFKVLRMALERPQGLPLALQLTPFFFKWRDRSPERANGLPKA 293
            ..:....  .|||..  |||||:|:
  Fly   151 RTISNDHNLQINESA--VLVNTVYY---------------------------------------- 173

Human   294 TQGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLIL 358
             .|.||::||.::|:.::|:....:.....||...|:||....:.| |::|:||...|::|::.|
  Fly   174 -SGAWKTRFSKKDTKLKVFHGDHNKKVYVRMMSHVGRFRIADHSYG-QIIEMPFDNSDLSMIIGL 236

Human   359 PKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSK 423
            |.....|:.:||     :|:...:.|.|..:.|.:|:|:|:....|.|.|:.:|:..:|| ..|.
  Fly   237 PLHNTYLSSIEK-----ILRTLSESLVENNVHVELPKFKIKYQTELVESLKKLGIHLIFS-NTSD 295

Human   424 LPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREV 488
            |.|::..| ....::...||:|:|:||.|:....::....:.:.......:||.||||:..||:
  Fly   296 LSGLLTNG-TGAKINHVVHKSFIEINERGASTGEASDHAESIQKKTRASTSFKVNRPFVFLIRD- 358

Human   489 PLNTIIFMGRV 499
             .:|:.|.|||
  Fly   359 -KHTVYFRGRV 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINC1	NP_001373231.1	serpinC1_AT3	70..504	CDD:381002	101/401 (25%)
Spn28Db	NP_001356884.1	SERPIN	22..368	CDD:238101	99/399 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100128
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.930