Sequence 1: | NP_005954.3 | Gene: | MYH1 / 4619 | HGNCID: | 7567 | Length: | 1939 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001285949.1 | Gene: | ck / 34882 | FlyBaseID: | FBgn0000317 | Length: | 2167 | Species: | Drosophila melanogaster |
Alignment Length: | 2233 | Identity: | 560/2233 - (25%) |
---|---|---|---|
Similarity: | 907/2233 - (40%) | Gaps: | 552/2233 - (24%) |
- Green bases have known domain annotations that are detailed below.
Human 27 AQNKPFDAKTSVFVVDPKESFVKATVQSREGGKVTAKTEAGATVTVKDD-QVFPMNPPKYDKIED 90
Human 91 MAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHI 155
Human 156 FSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLE 220
Human 221 DQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERS 285
Human 286 YHIFYQIMSNKKPDLIEMLLITTNPYDYAFVSQG-EITVPSIDDQEELMATDSAIEILGFTSDER 349
Human 350 VSIYKLTGAVMHYGNMKFKQKQREEQAEPDGTEV-----ADKAAYLQNLNSADLLKALCYPRVKV 409
Human 410 GNEYVTKGQTVQQVYNAVGALAKAVYDKMFLWMVTRINQQLDTKQPR---QYFIGVLDIAGFEIF 471
Human 472 DFNSLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTFIDFGMDLAACIELIE-KPMGIFS 535
Human 536 ILEEECMFPKATDTSFKNKLYEQHLGKSNNFQKPKPAKGKPEAHFSLIHYAGTVDYNIAGWLDKN 600
Human 601 KDPLNETVVGLYQKSAMKTLALLFVG--ATGAEAEAGGGKKGGKKKGSSFQTVSALFRENLNKLM 663
Human 664 TNLRSTHPHFVRCIIPNETKTPGAMEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKV 728
Human 729 LNASAIPEGQFIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQ 793
Human 794 AMCRGFLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKL-YFKIKPLLKSAETEKEMANMK 857
Human 858 EEFEKTKEELAKTEAK------RKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTK 916
Human 917 IQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKN 981
Human 982 LTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDD---LEGSLE 1043
Human 1044 ---------------QEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSG 1093
Human 1094 LQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISERLEEAG 1158
Human 1159 --GATSAQIEMNKKREAEFQK---MRRD------LEEATLQHEATAATLRKKHADSVAELGEQI- 1211
Human 1212 ----------DNLQ-----RVKQKLEK---------EKSEMKMEI-----DDLASNMETVSKAKG 1247
Human 1248 NL------------EKMCRALEDQLSE-----IKTKEEEQQRLINDLTAQR----ARLQTESGEY 1291
Human 1292 SRQL-------DEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHAL------------ 1337
Human 1338 QSSRHDCDLLR--EQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEE----------- 1389
Human 1390 LEEAKK--KLAQRLQDAEEHVEAVNAK--------CASLEKTKQRLQNEVEDLMID-----VERT 1439
Human 1440 NAACAALDKKQ-----------------------------------RNF-------DKILA-EWK 1461
Human 1462 -----QKCEETHAELE-------ASQKESR------SLST---ELFKIKNAYEESLDQ-----LE 1500
Human 1501 TLKRENKNL-----QQEISDLTEQIA--EGGKRIHELEKIKKQV------------EQEKSELQA 1546
Human 1547 A--------------------LEEA-------------------------EASLEHEEGKILRIQ 1566
Human 1567 LELNQVKSEVDRKIAEKDEEIDQMKRNHIR--IVESMQS----------TLDAEIRSRNDAIRLK 1619
Human 1620 KKMEGDL---------------NEMEIQL-----NHANRMAAE--------ALRNYRNTQAILKD 1656
Human 1657 TQLHL---------DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQ----------TERS 1702
Human 1703 RKI-----AEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGE--------MEDIIQEARN 1754
Human 1755 AEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTV--KD-----LQHRLDEAEQLALKGG 1812
Human 1813 KKQIQKLEARVRELEGEVE-SEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQ 1876
Human 1877 AKVKSYKRQAEEAEEQSNVNLSK 1899 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
MYH1 | NP_005954.3 | Myosin_N | 36..73 | CDD:280832 | 7/36 (19%) |
Myosin_head | 88..770 | CDD:278492 | 279/693 (40%) | ||
MYSc_Myh1_mammals | 100..770 | CDD:276875 | 273/681 (40%) | ||
Actin-binding. /evidence=ECO:0000250 | 659..681 | 11/21 (52%) | |||
Actin-binding. /evidence=ECO:0000250 | 761..775 | 7/13 (54%) | |||
Myosin_tail_1 | 850..1927 | CDD:279860 | 252/1396 (18%) | ||
RILP-like | 965..1098 | CDD:304877 | 30/150 (20%) | ||
MIT_CorA-like | <1299..>1411 | CDD:294313 | 24/138 (17%) | ||
DUF342 | <1506..1582 | CDD:302792 | 20/139 (14%) | ||
DUF342 | <1670..1767 | CDD:302792 | 22/119 (18%) | ||
TMPIT | 1744..>1853 | CDD:285135 | 25/124 (20%) | ||
ck | NP_001285949.1 | MYSc | 64..733 | CDD:214580 | 282/706 (40%) |
MYSc_Myo7 | 77..721 | CDD:276832 | 273/681 (40%) | ||
MyTH4 | <1138..1245 | CDD:214535 | 23/106 (22%) | ||
B41 | 1251..1467 | CDD:214604 | 37/234 (16%) | ||
FERM_B-lobe | 1355..1439 | CDD:271216 | 15/83 (18%) | ||
FERM_C1_MyoVII | 1461..1559 | CDD:270019 | 22/97 (23%) | ||
SH3 | 1560..1624 | CDD:302595 | 12/63 (19%) | ||
MyTH4 | 1701..1849 | CDD:214535 | 27/151 (18%) | ||
B41 | 1856..2068 | CDD:214604 | 46/231 (20%) | ||
FERM_M | 1966..2068 | CDD:278785 | 22/103 (21%) | ||
FERM_C2_MyoVII | 2064..2159 | CDD:270020 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |