DRSC/TRiP Functional Genomics Resources

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Protein Alignment MYF6 and twi

DIOPT Version :9

Sequence 1:NP_002460.1 Gene:MYF6 / 4618 HGNCID:7566 Length:242 Species:Homo sapiens
Sequence 2:NP_001033967.1 Gene:twi / 37655 FlyBaseID:FBgn0003900 Length:490 Species:Drosophila melanogaster


Alignment Length:196 Identity:44/196 - (22%)
Similarity:75/196 - (38%) Gaps:60/196 - (30%)


- Green bases have known domain annotations that are detailed below.


Human    31 SPLYPGSDGTLSPCQDQMPPEAGSDSSGEEHVLAPPGLQPPHCPGQCLIWACKTCKRKSAPTD-- 93
            ||.....||:.....|      |||:.|:       ..:.|.          :..|||.:.|:  
  Fly   316 SPACLADDGSAGSLLD------GSDAGGK-------AFRKPR----------RRLKRKPSKTEET 357

Human    94 -----RRKAATLRERRRLKKINEAFEALKRRTVANPNQRLPKVEILRSAISYIERLQDLLHRLDQ 153
                 :|..|.:|||:|.:.:|:||::|::.....|:.:|.|::.|:.|..||:.|..:|...| 
  Fly   358 DEFSNQRVMANVRERQRTQSLNDAFKSLQQIIPTLPSDKLSKIQTLKLATRYIDFLCRMLSSSD- 421

Human   154 QEKMQELGVDPFSYRPKQENLEGADFLRTCSSQWPSVSDHSRGLVITAKEGGASIDSSASSSLRC 218
                                   ...|:...:|....:..|...:::|...||..|      |:|
  Fly   422 -----------------------ISLLKALEAQGSPSAYGSASSLLSAAANGAEAD------LKC 457

Human   219 L 219
            |
  Fly   458 L 458

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MYF6NP_002460.1 Basic 3..98 CDD:416335 15/73 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 31..63 9/31 (29%)
bHLH_TS_MRF4_Myf6 93..156 CDD:381504 20/69 (29%)
twiNP_001033967.1 HLH 363..413 CDD:278439 17/49 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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