DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gug and AT1G09040

DIOPT Version :9

Sequence 1:	NP_001261581.1	Gene:	Gug / 46156	FlyBaseID:	FBgn0010825	Length:	2007	Species:	Drosophila melanogaster
Sequence 2:	NP_172378.1	Gene:	AT1G09040 / 837425	AraportID:	AT1G09040	Length:	911	Species:	Arabidopsis thaliana

Alignment Length:	995	Identity:	189/995 - (18%)
Similarity:	303/995 - (30%)	Gaps:	343/995 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QGEIRVGPGHQVN----------DVYAKLP------DYN-----PISSFPIDKE-------TDER 42
            |.|.|||...||:          .|:...|      .|:     |:....|||.       .|..
plant    34 QVEPRVGDEFQVDIPPMMSATKRAVFLSTPVALDDSSYSFLIGLPVQVMWIDKHRRGQGNGDDNV 98

  Fly    43 ELEESRWSPGVVADGDLLMFLRA--ARSMAAFQGMCDGGLEDGCLAASRDDTTINALDVLHDSGY 105
            ::.:|            |..|||  :|..|..:|..|...|     ..:..:.:.|:.|:..|
plant    99 DMNQS------------LKSLRAKKSRCSAKIRGKSDKNSE-----TKKQRSNLEAVPVIPSS-- 144

  Fly   106 DPGKALQALVKCPVSKGIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWK 170
                                .|.:.|...|:.||..|||||.:: |:.:.:|...|::.|||
plant   145 --------------------SWEDLEVASFVLGLYTFGKNFTQV-KNFMENKGIGEIMLFYY--- 185

  Fly   171 KTPGA-NNNRPHRRRRQSALRRNRVT----------RANNSNSNTPPKKEDTPEPQTATTATAAA 224
               |. .|:..:....:|..:|||..          |.....:...|...|.|:.|.....:.:.
plant   186 ---GKFYNSAKYHSWSESRKKRNRKCVFGRTLYSGWRQQQLLTRLMPSIPDEPQKQILVDVSKSF 247

  Fly   225 TAASETASRSSPAVSKEENSSLTEDDASECDSDSSLTHKRDESPSRMRTRNKQQNNNSSTSSGNN 289
            ...:.|..:...||.......|..|..:.......||         :.|....:.....|.|..:
plant   248 AEGTITLEKYVSAVKNLVGLRLLVDAVAIGKEKEDLT---------VPTSTPMKTKPWFTVSSKS 303

  Fly   290 TAGNGGGNATSISSGSTGGGAAGGNSSSKDQSANAVANGKRPK---RG--SETPD---------- 339
            :...|.|:..|::|........|.:..||.:..:.......|:   ||  |:.|:
plant   304 SLVPGEGDYNSLTSAGIINQLTGCSRLSKARCNDIFWGAVWPRLLARGWHSQQPEDRGYFKSKDY 368

  Fly   340 ----------------VSGGASVDS-PKTPTKAVAESSANKRKGGKQDTPNKKKRTEQESNEPSA 387
                            |.|....|| ....||.|:|....:.:.|.........::::|| .||
plant   369 IVFIVPGVKKFSRQELVKGDHYFDSVSDILTKVVSEPELLENETGGVAAELSSDKSDEES-VPS- 431

  Fly   388 HEENAIKEKRKRPDSP--------------------------VESMNSD----SRPDSVLDDGES 422
               ::::.:..|  ||                          :.::|::    |.|:..|:..:|
plant   432 ---DSLRHRYLR--SPCSNRGTLGMKFTVVDTSLATGGKLCDLRNLNAECLVVSEPNVRLEVKDS 491

  Fly   423 ----NTTDTTTAEQQSTK--DSKETVS--------------CKEER-----EMVTNDLEAK---- 458
                |:.|:...|:...:  |:|..|.              |::..     ..:.:| |.|
plant   492 PVLKNSLDSQNVEKSQVRPLDAKNQVDDPMRFTIIDTSVDHCEKSSGFRRWRYLPSD-ETKRGHV 555

  Fly   459 AEEKAIKAEALAEDSKDSA---IKNMD---EETNIQAPSSADTSLVDGPNPNALPSPVAAPITMK 517
            ..:..||.|...|..||.:   ||:..   .|||..|.:|                   ||...:
plant   556 GADSGIKEEKTLEKVKDPSKRVIKHRSTPRAETNYHAVNS-------------------APYLKR 601

  Fly   518 VPTIATVEALNASVDRKEAIEKMESCDSDPEMLKKLATIKQEVSPQQQQ---------------- 566
                   ..|:|.:.|:..:.|....|.|.:|...|.:.:|.:...|||
plant   602 -------RRLSACISRESPVSKHIPGDDDTKMTVCLESEQQSICVVQQQTSTCEEMNQDKETVPL 659

  Fly   567 --HMQQQSQQQMQQQLAP----VGIPQPPSCPPSESVYIKKEPMEDSMDATCNQNSNEPQDLKV- 624
              ||:.:|.|..:....|    |.|.:.....||                  ..|||...|...
plant   660 VEHMKLKSDQSKKTGTGPSSLLVEIQETTEIEPS------------------GLNSNTGVDKNCS 706

  Fly   625 --KIEIKNEDALKHSAGGLPPSGPCAPPSA----------------LHPLSGAPVESGQ------ 665
              ||...:|.         .|:|.|:...:                |..:||....|..
plant   707 PEKISTSHEQ---------KPNGLCSVSKSDKKRASNDLEQKQALELPSISGLNNRSSSNDLGTT 762

  Fly   666 EPLHLQHMPHGQVTTQPPPGYLIDGQLKYGPSGQGVPPQPPQLHSDAAGGVSGAPPGAPTTPQKY 730
            :.|......|||.....            ||..|....:|....:..|
plant   763 QELGSSEQQHGQQNNTD------------GPRRQSTRKRPLTTRALEA----------------- 798

  Fly   731 PPEMEMKF-APQDLKYPPPPPLDALKYSQEMQAAAAAAAAAGKYDMKYMMEQQGKYNVELSAAHQ 794
               ||..| ..:.:|....|.....:.|.:.:.:|.|....|..|:::..|.:   |:.:..|
plant   799 ---MESDFLTTKRMKSTTKPEPRKRESSTKKKRSAKACNRNGSADLEHRREDR---NIFIWKA-- 855

  Fly   795 PPSKPGYQDSLKIPDIKPGF 814
            |.|||..|    |.|.||.:
plant   856 PTSKPLDQ----IEDTKPRY 871

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gug	NP_001261581.1	ELM2	9..68	CDD:279754	18/88 (20%)
		SANT	125..172	CDD:197842	16/46 (35%)
		SANT_MTA3_like	126..171	CDD:212559	16/44 (36%)
		Sec_Non_Glob	344..>440	CDD:275213	23/132 (17%)
AT1G09040	NP_172378.1	SANT	145..185	CDD:304392	14/40 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13859
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100