DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gug and mta1

DIOPT Version :9

Sequence 1:	NP_001261581.1	Gene:	Gug / 46156	FlyBaseID:	FBgn0010825	Length:	2007	Species:	Drosophila melanogaster
Sequence 2:	XP_005158917.1	Gene:	mta1 / 794477	ZFINID:	ZDB-GENE-131121-353	Length:	617	Species:	Danio rerio

Alignment Length:	259	Identity:	75/259 - (28%)
Similarity:	119/259 - (45%)	Gaps:	34/259 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QGEIRVGPGHQVNDVYAKLPDYNPISSFPIDKETDERE---LEESRWSP-GVVADGDLLMFLRAA 66
            :||||||..:|.:           |:....:.|.|:||   |||..|.| ..:.:..:..||..|
Zfish   147 KGEIRVGNKYQAD-----------ITDLLKEGEEDDRELEKLEEKVWDPSNPLTEKQIDQFLVVA 200

  Fly    67 RSMAAFQGMCD-------GGLEDGCLAASRDDTTINALDVLHDSGYDPGKALQALVK--CPV-SK 121
            ||:..|....|       ..|.....|||||.|..:|:|.||.:|||..:|:.|||.  .|| .:
Zfish   201 RSVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHKNGYDMTRAIAALVPQGGPVLCR 265

  Fly   122 GIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPGANNNRPHRRRRQ 186
            ...::|:..|...|.:.|.::||:|..|.:|.||.|....::|:||:||.|    :....::|.:
Zfish   266 DEMEEWSASEANLFEEALEKYGKDFTDIQQDFLPWKSLTSIIEYYYMWKTT----DRYVQQKRLK 326

  Fly   187 SALRRNRVTRANNSNSNTPPKKE---DTPEPQTATTATAAATAASETA--SRSSPAVSKEENSS 245
            :|...:::.:....|.|.|...:   ::.:|.....|.|...|..:..  .|:..:...|..||
Zfish   327 AAEAESKLKQVYIPNYNKPNPNQLSVNSVKPGLVNGAGALPGAPGQPVGLGRACESCYSESTSS 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gug	NP_001261581.1	ELM2	9..68	CDD:279754	18/62 (29%)
		SANT	125..172	CDD:197842	17/46 (37%)
		SANT_MTA3_like	126..171	CDD:212559	16/44 (36%)
		Sec_Non_Glob	344..>440	CDD:275213
mta1	XP_005158917.1	BAH_MTA	3..171	CDD:240060	9/34 (26%)
		ELM2	150..202	CDD:279754	18/62 (29%)
		SANT	269..316	CDD:197842	17/46 (37%)
		SANT_MTA3_like	270..315	CDD:212559	16/44 (36%)
		ZnF_GATA	375..430	CDD:214648	4/16 (25%)
		ZnF_GATA	379..437	CDD:238123	3/12 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D802091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920