DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gug and F10E7.11

DIOPT Version :9

Sequence 1:	NP_001261581.1	Gene:	Gug / 46156	FlyBaseID:	FBgn0010825	Length:	2007	Species:	Drosophila melanogaster
Sequence 2:	NP_001379868.1	Gene:	F10E7.11 / 174170	WormBaseID:	WBGene00017352	Length:	239	Species:	Caenorhabditis elegans

Alignment Length:	274	Identity:	68/274 - (24%)
Similarity:	101/274 - (36%)	Gaps:	87/274 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 NDVYAKLPD-------YNPI---SSFPIDKETDERE-----------LEESRWSPGVVADGDL-- 59
            :|.||..||       .:|:   :..|:..|....|           ::::......|.|..|
Worm     8 DDDYAPPPDPWKRSIRVDPVLFQADVPLFNEATVEESAREDDTILWTIDQTNQPSDEVIDNYLKD 72

  Fly    60 LMFLRAARSMAAFQGMCDGGLEDGCLAASRDDTTINALDVLHDSGYDPGKALQAL----VKCPV- 119
            ::.||.|..    |.....|.|      ||||.  :||..|:.|.:|..||.::.    :..|.
Worm    73 VVGLRKAHD----QPCPPAGTE------SRDDE--DALCALYRSNFDTEKAKESFPFPHINAPFR 125

  Fly   120 -----SKGIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPG----- 174
                 :.|.|    |.|.|.|.:.|..:||:|..|.:..||::...||:|:||.||.|||
Worm   126 TVRSDALGFD----ESEAKAFEESLELYGKDFSLIRRLRLPYRKVGELIEYYYQWKLTPGYRVWR 186

  Fly   175 ------ANNNRPHRRRRQSALRRNRVTRANNSNSNTPPKKEDTPEPQTATTATAAATAASETASR 233
                  |...:||    .||....:..:..:.|..|...:....||.|:
Worm   187 DAHPQHAPVVQPH----LSAAWHQQAAQLEDQNGQTGFVEASFSEPSTS---------------- 231

  Fly   234 SSPAVSKEENSSLT 247
                   ||.|:||
Worm   232 -------EEPSTLT 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gug	NP_001261581.1	ELM2	9..68	CDD:279754	15/72 (21%)
		SANT	125..172	CDD:197842	18/46 (39%)
		SANT_MTA3_like	126..171	CDD:212559	17/44 (39%)
		Sec_Non_Glob	344..>440	CDD:275213
F10E7.11	NP_001379868.1	ELM2	22..73	CDD:396160	7/50 (14%)
F10E7.11	NP_001379868.1	SANT_MTA3_like	134..177	CDD:212559	17/46 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910