DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gug and Mta3

DIOPT Version :9

Sequence 1:	NP_001261581.1	Gene:	Gug / 46156	FlyBaseID:	FBgn0010825	Length:	2007	Species:	Drosophila melanogaster
Sequence 2:	XP_038934036.1	Gene:	Mta3 / 100362346	RGDID:	1306803	Length:	637	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	79/262 - (30%)
Similarity:	119/262 - (45%)	Gaps:	43/262 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QGEIRVGPGHQVNDVYAKLPDYNPISSFPIDKETDERE---LEESRWSP-GVVADGDLLMFLRAA 66
            :|||||||.:|     |.:||..|      :.::||||   ||...|.| ..:.|..:..||..|
  Rat   147 KGEIRVGPKYQ-----ADIPDVLP------EGDSDEREQSKLEVKVWDPNSPLTDRQIDQFLVVA 200

  Fly    67 RSMAAFQGMCD-------GGLEDGCLAASRDDTTINALDVLHDSGYDPGKALQALVKC--PV-SK 121
            |::..|....|       ..|.....|||||.|..:|:|.|:..|||...|:..||..  || .:
  Rat   201 RAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLYRHGYDLSSAISVLVPLGGPVLCR 265

  Fly   122 GIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPG-ANNNRPHRRRR 185
            ...::|:..|...|.:.|.::||:|..|.:|.||.|....::|:||:||.|.. ....|......
  Rat   266 DEMEEWSASEASLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTTDRYVQQKRLKAAEA 330

  Fly   186 QSALRR-----------NRVTRANNSNSNTPPKKEDTP-EPQTATTATAA----ATAASETASRS 234
            :|.|::           |::: ::|..:.|......|| :||:|....|.    ||.:.:..|..
  Rat   331 ESKLKQVYIPTYSKPNPNQIS-SSNGKAGTVNGAVGTPFQPQSALLGRACESCYATQSHQWYSWG 394

  Fly   235 SP 236
            .|
  Rat   395 PP 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gug	NP_001261581.1	ELM2	9..68	CDD:279754	22/62 (35%)
		SANT	125..172	CDD:197842	17/46 (37%)
		SANT_MTA3_like	126..171	CDD:212559	16/44 (36%)
		Sec_Non_Glob	344..>440	CDD:275213
Mta3	XP_038934036.1	BAH_MTA	3..170	CDD:240060	12/33 (36%)
		ELM2	150..201	CDD:396160	21/61 (34%)
		SANT_MTA3_like	270..315	CDD:212559	16/44 (36%)
		ZnF_GATA	376..421	CDD:214648	5/21 (24%)
		MTA_R1	460..536	CDD:407344
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D802091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920