DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gug and mta3

DIOPT Version :9

Sequence 1:	NP_001261581.1	Gene:	Gug / 46156	FlyBaseID:	FBgn0010825	Length:	2007	Species:	Drosophila melanogaster
Sequence 2:	XP_021335673.1	Gene:	mta3 / 100003254	ZFINID:	ZDB-GENE-030131-6485	Length:	709	Species:	Danio rerio

Alignment Length:	432	Identity:	105/432 - (24%)
Similarity:	147/432 - (34%)	Gaps:	140/432 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 QGEIRVGPGHQVNDVYAKLPDYNPISSFPIDKETDERE---LEESRWSPGV-VADGDLLMFLRAA 66
            :|||||||..|     |.:|:...      :.|.|:|:   ||...|.|.. :.:..:..||..|
Zfish   147 KGEIRVGPRFQ-----ADVPEMLQ------EGEADDRDQSKLEMKMWDPECPLTNKQIDQFLVVA 200

  Fly    67 RSMAAFQGMCD-------GGLEDGCLAASRDDTTINALDVLHDSGYDPGKALQALVK--CPV-SK 121
            |::..|....|       ..|.....|||||.|..:|:|.||..|||...||..||.  .|| .:
Zfish   201 RAVGTFARALDCSSSVRQPSLHMSAAAASRDITLFHAMDTLHRHGYDLSSALSVLVPQGGPVLCR 265

  Fly   122 GIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPGANNNRPHRRRRQ 186
            ...::|:..|...|.:.|.::||:|..|.:|.||.|....::|:||:||.|        .|..:|
Zfish   266 DEMEEWSSSEANLFEEALEKYGKDFNDIRQDFLPWKSLTSIIEYYYMWKTT--------DRYVQQ 322

  Fly   187 SALRRNRVTRANNSNSNTPPKKEDTPEPQTATTATAAATAASETASRSSPAVSKEENSSLTEDDA 251
            ..|:                                ||.|.|:......|
Zfish   323 KRLK--------------------------------AAEAESKLKQVYIP--------------- 340

  Fly   252 SECDSDSSLTHKRDESPSRMRTRNKQQNNNSSTSSGNNTAGNGGGNATSISSGSTGGGAAGGNSS 316
                                 |.||...|..|.|:|.....||.  |....|..|.||.....|.
Zfish   341 ---------------------TYNKPNPNQISVSNGKMATVNGA--AAGTGSFHTAGGGRACESC 382

  Fly   317 SKDQSANAVANGKRPKRGSETPDVS--------------GGASVDSPKTPTKAVAESSANKRKGG 367
            ...|||...:.|        .|::.              ||.     |.|::|         :|.
Zfish   383 FAVQSAQWYSWG--------PPNMQCRLCVSCWMYWKKYGGL-----KMPSRA---------EGA 425

  Fly   368 KQDTPNKKKRTEQESNEPSAHEENAIKEKRKRPDSPVESMNS 409
            ::.||......|..|....|.:.:.:...| ...||..||.:
Zfish   426 EEKTPPSPAPNESRSRGHCARQSSHMVPIR-NSGSPKSSMKT 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gug	NP_001261581.1	ELM2	9..68	CDD:279754	18/62 (29%)
		SANT	125..172	CDD:197842	17/46 (37%)
		SANT_MTA3_like	126..171	CDD:212559	16/44 (36%)
		Sec_Non_Glob	344..>440	CDD:275213	14/66 (21%)
mta3	XP_021335673.1	BAH_MTA	3..171	CDD:240060	11/34 (32%)
		ELM2	150..201	CDD:307553	17/61 (28%)
		SANT_MTA3_like	270..315	CDD:212559	16/44 (36%)
		ZnF_GATA	374..425	CDD:214648	13/72 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D802091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920