Protein Alignment CG31195 and GPR179

DIOPT Version :10

• Sequence 1: NP_732553.2
• Gene: CG31195 / 46155
• FlyBaseID: FBgn0051195
• Length: 807
• Species: Drosophila melanogaster
• Sequence 2: NP_001004334.3
• Gene: GPR179 / 440435
• HGNCID: 31371
• Length: 2367
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 73/319 - (22%)
• Similarity: 116/319 - (36%)
• Gaps: 105/319 - (32%)

  Fly   479 GAKEQFENEAKMAVRLANFISAFLQVSDPNEVYSGKRVADKPLTEDQMIGETL--AIVLGDSKVW 541
            |.....:..|....:.|||::..||.:|         :.:..:.||....:.|  ::..||.:|:
Human    90 GLPPSLQGAAGTLAQAANFLNMLLQAND---------IRESSVEEDVEWYQALVRSVAEGDPRVY 145

  Fly   542 SATMLWERNKFTNRTYFAPYAYKTELNTRKFKVEDLARLNKTHELYTEKKYFKFLKQRWNTNFD- 605
            .|.:.:......:....|..|.:|                      .|:...:.|...|....:
Human   146 RALLTFNPPPGASHLQLALQATRT----------------------GEETILQDLSGNWVQEENP 188

  Fly   606 --DLETFYMKIKIRHNETGEYQQKYEHYPNSYRAANIKHGYWTQPQFDCDGYV------------ 656
              ||:|..:|.::..|:.|                ::....|.|    .||||
Human   189 PGDLDTPALKKRVLTNDLG----------------SLGSPKWPQ----ADGYVGDTQQVRLSPPF 233

  Fly   657 ---------KKWLVTYAVPFFGWDSLKVKL--EFKGVVAVSMDMLQLDINQC---PDWYYEPNAF 707
                     ..||:|.:..|:|   ||..|  |.:|.|.:.:|:..:|||||   |.||
Human   234 LECQEGRLRPGWLITLSATFYG---LKPDLSPEVRGQVQMDVDLQSVDINQCASGPGWY------ 289

  Fly   708 KNTHKCDEQSSYCVPIMGRGYETGGYKCECLQGYEYPFEDLITYY----DGQLVEAEYQ 762
            .|||.||..|:.|||:..:|:..|.|.|.|..|          :|    .|.|.|:::|
Human   290 SNTHLCDLNSTQCVPLESQGFVLGRYLCRCRPG----------FYGASPSGGLEESDFQ 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31195	NP_732553.2	HK_sensor	<592..689	CDD:365792	25/122 (20%)
GPR179	NP_001004334.3	Cache-like region. /evidence=ECO:0000250|UniProtKB:Q5T848	62..245		33/205 (16%)
		EGF_CA	278..327	CDD:238011	24/64 (38%)
		7tmC_GPR158-like	387..635	CDD:320420
		TM helix 2	416..437	CDD:320420
		TM helix 3	446..470	CDD:320420
		TM helix 4	490..510	CDD:320420
		TM helix 5	539..565	CDD:320420
		TM helix 6	573..596	CDD:320420
		TM helix 7	605..630	CDD:320420
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	731..818
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	869..932
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1039..1083
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1098..1198
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1247..1431
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1537..1557
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1577..1672
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1723..1757
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1823..1852
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1886..2108
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2133..2212
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2308..2367