DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31195 and Gpr179

DIOPT Version :9

Sequence 1:	NP_732553.2	Gene:	CG31195 / 46155	FlyBaseID:	FBgn0051195	Length:	807	Species:	Drosophila melanogaster
Sequence 2:	NP_001074689.1	Gene:	Gpr179 / 217143	MGIID:	2443409	Length:	2293	Species:	Mus musculus

Alignment Length:	277	Identity:	69/277 - (24%)
Similarity:	114/277 - (41%)	Gaps:	57/277 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   479 GAKEQFENEAKMAVRLANFISAFLQVSDPNEVYSGKRVADKPLTEDQMIGETL--AIVLGDSKVW 541
            |.....:..|....:.|||::..||.:|         :.:..:.||....:.|  ::..||.|.:
Mouse    90 GVPPVLQRAAGTLAQAANFLNMLLQAND---------IRESSVEEDVEWYQALVRSVAEGDPKAY 145

  Fly   542 SATMLWERNKFTNRTYFAPYAYKTELNTRKFKVEDLARL-----NKTHELYTEKKYFKFLKQRWN 601
            .|.:.:..         ||.|...:|..:..::.|...|     ||..|               .
Mouse   146 RALLTFNP---------APGASHLQLALQATRMGDETVLQDLSGNKVQE---------------E 186

  Fly   602 TNFDDLETFYMKIKIRHNETGEYQQKYEHYPNSYRAANIKHGYWTQPQFDC-DGYVKK-WLVTYA 664
            |..:||:...::.::..|:............:.| ..:|:....:.|..:| :|.::. ||||.:
Mouse   187 TPGEDLDRPVLQKRVLTNDLRSLDSPKWPRGDGY-VGDIQQVKLSPPFLECHEGQLRPGWLVTVS 250

  Fly   665 VPFFGWDSLKVKL--EFKGVVAVSMDMLQLDINQC---PDWYYEPNAFKNTHKCDEQSSYCVPIM 724
            ..|:|   ||..|  |.:|.|.:.:|:..:|||||   |.||      .|||.||..|:.|||:.
Mouse   251 ATFYG---LKPDLTPEVRGQVQMDIDLQSVDINQCASGPGWY------SNTHLCDLNSTQCVPLE 306

  Fly   725 GRGYETGGYKCECLQGY 741
            .:|:..|.|.|.|..|:
Mouse   307 SQGFVLGRYLCRCRPGF 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31195	NP_732553.2	None
Gpr179	NP_001074689.1	EGF_CA	278..327	CDD:238011	23/52 (44%)
Gpr179	NP_001074689.1	7tm_3	392..632	CDD:278433
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR32546
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100