DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(3)02640 and hmbs

DIOPT Version :9

Sequence 1:	NP_612103.1	Gene:	l(3)02640 / 46140	FlyBaseID:	FBgn0010786	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_012821804.1	Gene:	hmbs / 448096	XenbaseID:	XB-GENE-5918290	Length:	358	Species:	Xenopus tropicalis

Alignment Length:	305	Identity:	163/305 - (53%)
Similarity:	213/305 - (69%)	Gaps:	14/305 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AQEK--VIRVGSRKSELALIQTKHVIGRLQKLYPKQKFEIHTMSTFGDRVLNVSLPKIGEKSLFT 65
            |:|.  |||||:|||:||.|||..|:..|.|.:|...|:|..|||.||::|:.:|.|||||||||
Frog    11 AEENKHVIRVGTRKSQLARIQTDSVVEMLSKRFPSTHFDIVAMSTTGDKILDTALSKIGEKSLFT 75

  Fly    66 RDLEDALRNGGVDFVVHSLKDLPTALPTGMAIGAVLEREDARDALVLRENFKGHTIASLPKGSVI 130
            ::||:||....||.||||||||||:||.|..||||.:||:..||:|......|:|:::||:.|||
Frog    76 KELENALERNEVDLVVHSLKDLPTSLPPGFTIGAVCKRENPYDAVVFHPKRYGNTLSTLPEKSVI 140

  Fly   131 GTSSLRRTAQIRRMYPHLTVCDIRGNLNTRLAKLDAADSKFSGIILAQAGLVRMGWMSRISQVLE 195
            |||||||.||:::.:|||...|||||||||:.|||..:. ||.||||.|||.||||.:||.|:|.
Frog   141 GTSSLRRAAQLKKKFPHLEFKDIRGNLNTRMKKLDEKED-FSAIILAAAGLRRMGWENRIGQILT 204

  Fly   196 PTDLLYAVGQGALAVECRANDDQVLAMLQKLMCLNTTCRILAERSFLKTLGGGCSAPVAVWSNLK 260
            ..:.||||||||||:|.||.|..:|:|:..|....|..|.:|||:|:|.|.||||.||||.:.:|
Frog   205 SDECLYAVGQGALAIEVRAKDQDILSMVSALQDPETVLRCIAERAFMKRLEGGCSVPVAVNTVVK 269

  Fly   261 GEPLNGNSQEVGLSLTGAVWSLDGAIEIRNHLACALN--EQKLEG 303
                  :||   |.|||||:||||:..::..:...:|  :|::||
Frog   270 ------DSQ---LYLTGAVYSLDGSDSLKETMQSCINFPQQEVEG 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)02640	NP_612103.1	hemC	6..289	CDD:234612	157/284 (55%)
l(3)02640	NP_612103.1	PBP2_HuPBGD_like	7..296	CDD:270363	157/288 (55%)
hmbs	XP_012821804.1	PBP2_HuPBGD_like	17..296	CDD:270363	157/288 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	236	1.000	Domainoid score	I2286
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H158
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1189095at2759
OrthoFinder	1	1.000	-	-		FOG0004130
OrthoInspector	1	1.000	-	-		oto103782
Panther	1	1.100	-	-	LDO	PTHR11557
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2873
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.020