Protein Alignment Nup214 and LNO1

DIOPT Version :9

• Sequence 1: NP_652039.2
• Gene: Nup214 / 46091
• FlyBaseID: FBgn0010660
• Length: 1711
• Species: Drosophila melanogaster
• Sequence 2: NP_001117499.2
• Gene: LNO1 / 842002
• AraportID: AT1G55540
• Length: 1819
• Species: Arabidopsis thaliana
• Alignment Length: 2040
• Identity: 443/2040 - (21%)
• Similarity: 729/2040 - (35%)
• Gaps: 613/2040 - (30%)

  Fly     9 EDTQDFQFKLHHKIVAFKKCGEPRS------NVNL-------LAVSSSRGLLFAGSPTQPELKVI 60
            |||:..:...:.  ..|::.|||.|      ..:|       ||:|....:||....:  ...|.
plant     8 EDTEGDRISTND--YYFERIGEPISIKEDDAQYDLENPPSQPLAISERHAVLFVAHSS--GFFVG 68

  Fly    61 IVKDLVNAKSTAQQPQARL----VPLPSIP----NYIACSSDGNLLAVNHTQNGTSLLSIYAVLS 117
            ...|:::|...:.....::    :.|..:|    ..::.|:|.::|||....:    :..::|.|
plant    69 RTNDVISASKNSNGNGDKVFIQDLSLVDVPVGDVRILSLSADDSILAVTVAAD----IHFFSVDS 129

  Fly   118 FMTPDVRPVYNIRLAAEDHVHGVQLLWNPVLPNSLAVVLSNGALAMYALKEGGNFEMHSLDKNQQ 182
            .:..|.:|.::........|...:  |.....:|. :||||.....:.:....  ..|.:|....
plant   130 LLKKDAKPSFSYSPDESGFVKDFR--WRRNDKHSY-LVLSNTGKLFHGIDNAP--PRHVMDAVDA 189

  Fly   183 VKCGCWSPKGKQIVLGFPGGTVKQFKPDLTLAKTLLCPPN--IHDAPFDTI----AIQW------ 235
            |:   ||.||..|.:. ...:::.|.......:.:....:  |.|:..|..    :|:|
plant   190 VE---WSSKGSYIAVA-QDNSLRIFSSKFNEKRCIALSFDSWIGDSDEDCFVKVDSIRWVRNNCI 250

  Fly   236 -LSTFQFAVIFLQHGEDCSPSLYILNAPKA----GAPSYI--NYYDI--CYSMN-------GPRN 284
             |..||     |..|.:.:..:.::.:|..    |:.:.:  ::.|:  | ||:       ||
plant   251 LLGCFQ-----LIEGREENYLVQVIRSPDGKISDGSTNLVALSFSDLFPC-SMDDLVPVGVGP-- 307

  Fly   285 HQFVFSHVPQWNLLLVVSANGVEVGI-MRSTEAGDTPAWQQLTLLDEARI--EMPLSEDKDETFP 346
             ..:||::.|..|.:..:...::..| :....:||..:...:..:|....  .:.|.|:.|:...
plant   308 -HLLFSYIDQCKLAVTANRKSIDEHIVLLDWSSGDDKSAVSVVDIDRETFLPRIGLQENNDDNTV 371

  Fly   347 LGFAFDTSTTHQLTINE-------KKLQTMPMVHVLSSDGELLSFNFLNVLPTAVSVCSPPPPVA 404
            :|...| ..:.:.|:|.       |:||...::..|:.:|:|:.||..:|        :..|..:
plant   372 MGLCID-RVSIEGTVNVRSGDDELKELQPYFVLVCLTLEGKLVMFNVASV--------AGRPASS 427

  Fly   405 DTSGQFKPLNMLLASEEEEQPAWA---------ASPSKAPAATPAASSDISFAFTPNTVTSTPAP 460
            ||.         |||..:.:.|:.         .|..|......|..:|.....|....|....|
plant   428 DTD---------LASSSDIEDAYTPLIEDDLSKQSSEKHQQLNIAVQNDQKHLNTEKFSTEQRLP 483

  Fly   461 SKDKQPSLFSGFGAA---------------------AAKAPAPQLSFGTAPTSSPVSFGAPTTNA 504
            :::.....|....::                     |.::..|:|| ||:....|:|.|..|..
plant   484 NENIFSKEFESVKSSVSGDNNKKQEPYAEKPLQVEDAQQSMIPRLS-GTSFGQLPMSLGYDTNK- 546

  Fly   505 AKPTTPFGGFGTQ------------ATTTAM---GSMFSASGANAFGGMALNKPAIASVTPRTAA 554
                  |.|||..            |.:.:|   .::.|.|.|..||...|....:.|....::.
plant   547 ------FAGFGPALPVSEKLQKDIFAQSNSMHLQANVESKSTAAFFGSPGLQNAILQSPQNTSSQ 605

  Fly   555 PGSTVPATPASAPANKPLYTVPLTFTPVDTKPAT---SAPPQIADESLKPDDT------------ 604
            |.|:..:.......:.|..::..|......:..|   :.|..|.|:|::..:|
plant   606 PWSSGKSVSPPDFVSGPFPSMRDTQHKQSVQSGTGYVNPPMSIKDKSVQVIETGRVSALSNLSPL 670

  Fly   605 --------------EPIIK---DMIALQIE-AFSKDIQKQKEQTKELLKGIAAPSALRAYAKRLD 651
                          |||..   ..::.|:: :|.|....|:.:|.      .:...||......:
plant   671 LGQNQDTNEGVEKIEPIPSIRASQLSQQVKSSFEKSASHQQHKTP------LSTGPLRLEHNMSN 729

  Fly   652 DLQELNEQAKDVE-------------------FELDVQGLRQGLNEAYAIVAECR-GKLEIY-RK 695
            ....:||.|::::                   .:.:|:.|.|||.   ::..:|: .|..|: ::
plant   730 QPSNINEMAREMDTLLQSIEGPGGFKDSCAFILKSNVEELEQGLE---SLAGKCQTWKSTIHEQQ 791

  Fly   696 PEITRLMNSSSCDPSGRRMLARLQSYVAANEAQLRLAQQHVDLQWEQFQDVVRRNSKSRMHMPCL 760
            .||..|::.:.      ::||: ::|:..      :.:|..|.|:.|..:..:.|       |.|
plant   792 AEIQHLLDKTI------QVLAK-KTYMEG------MYKQTADNQYWQLWNRQKLN-------PEL 836

  Fly   761 EGIYQRLTRLQNLTSNQRIVQNNIKSKLK-------------ERGLLQAALLDQEKSRTRTNEAV 812
            |...|.:.:|....::|.|......::|:             .||:         .:|:..:..|
plant   837 EAKRQHIMKLNKDLTHQLIELERYFNRLELDRYNEDGGHPVARRGV---------PNRSAPSRRV 892

  Fly   813 DTLTDSILTMSLSQVVDSNAAKLTRERLQKIRNIVQLQKINVICPQR------------------ 859
            .:|.....||| ||:.   ||:...|.|.|     |:..:.:..|.:
plant   893 QSLHSLHNTMS-SQLA---AAEQLSECLSK-----QMTYLKIDSPVKKNVKQELFETIGIPYDAS 948

  Fly   860 ---PDRVGLK----------SEVILETKRRAEQIKRAAAK---PATANK---------YTQAAVA 899
               ||.|..|          |.:.....:::.|.:.:|.|   |.||.:         :..||..
plant   949 FSSPDAVKAKNASSAKNLLLSSIPASINQQSRQRQSSAMKNSDPETARRRRESLDRVIFNWAAFE 1013

  Fly   900 PPSPP---DVAPTPAVAPMPQATVTVAPPLPKPMPSIPSVVEKP--GVPTHPTTPVAT------- 952
            ||...   .:........|.|.||     |.:.:.|..:..::.  .|..|.:..|::
plant  1014 PPKTTVKRMLLQEQQKTGMNQQTV-----LSERLRSANNTQDRSLLHVKDHASPVVSSNKGIMES 1073

  Fly   953 ---PFSFSQSIPFVKTSTVTPTTN---TVTPGEAAKPGLSIFGGSTISSFSFGGGAAKSALSFGT 1011
               ..|.:||.|| ||....|.:|   |::|..|:||           ||::.|..:.:..|:.
plant  1074 FQQDTSEAQSTPF-KTRPPMPQSNSPFTISPISASKP-----------SFNWSGNKSSNTTSYA- 1125

  Fly  1012 GSPAVAAPTPKPNPLSAVEKPTPEPTKPKEQKAAESKEFKAVQPETEESKVPQKPKA-----ETE 1071
                                        :|...::.|:.:.|......|.:|::|.|     :||
plant  1126 ----------------------------EESAPSQIKDTRTVSQPGGSSFLPKRPVASTVLEQTE 1162

  Fly  1072 NKSFGF-------GGFTGT-GGTVG--NTSSSPFSFGGLGSSLGFGGTAAAVPKSEPSSTATTSV 1126
            .|:..|       ..|..| .|:|.  :|:||...|   .||.|||...:.:....|:|:.::..
plant  1163 KKAGEFKFSEAKANAFVETAAGSVQRLSTTSSGSDF---ESSKGFGAQFSTMSSGAPASSFSSKS 1224

  Fly  1127 A---TSASTAPFGIFS-AALAKPSNSEPITTVTSNTTTITSKPTN------VIASSSVTDAP--- 1178
            .   .|:|:.|...|: .|:..|.:..|:.: ||...|.:|.|.:      |.||..::.||
plant  1225 LFGFNSSSSIPGDKFTFPAVTAPLSGTPLDS-TSTLFTASSAPVSSSSQDPVPASIPISSAPVPQ 1288

  Fly  1179 --SVTTTNAV--TSSTDPIGGLFSSVTI----CKPNTPADTTKPANIFGGGLSAGSFSFGGTIDA 1235
              |||:|:.|  |....|.|...:||.:    ..|:||:.:..|...|...|.|.|.|....:.:
plant  1289 TFSVTSTSTVSATGFNVPFGKPLTSVKVDLNQAAPSTPSPSPGPTAGFTFNLPALSPSSPEMVSS 1353

  Fly  1236 SKG---LFGSTKPV-------ATAPTSVTEAN--------NKTDPISTTPSA-----ISTTTATT 1277
            |.|   ||..:.|.       |:|.:|:|:::        :.|.|| |.|.|     :||.::..
plant  1354 STGQSSLFPPSAPTSQVSSDQASATSSLTDSSRLFSSTSLSSTPPI-TPPDAFQSPQVSTPSSAV 1417

  Fly  1278 TVSSPA---VVPAAVTAAVPATSST-------TVT--------------SSTAVPGSAFSFSNAF 1318
            .::.|.   ..|.|.::::.:|.||       |.|              .:|..|.|:..|.:.|
plant  1418 PITEPVSEPKKPEAQSSSILSTQSTVDSVANATKTQNEPLPVKSEISNPGTTVTPVSSSGFLSGF 1482

  Fly  1319 ST---LSAGGAAAPT------------TSASAPLAAKSPTATSTGNNSSNSV------------- 1355
            |:   .|....|||:            :|..||..|.|||:.|......:.|
plant  1483 SSGTQSSLASMAAPSFSWPGSSQPQQLSSTPAPFPASSPTSASPFGEKKDIVDTQEDEMDEEAPE 1547

  Fly  1356 -----------FGG-GFAVATSTAAPVASPFQSAAKSPVSSANIFGSIPKAETSVFGGATTAPSN 1408
                       ||| |.....:..||..:||...                     ||.|||..||
plant  1548 ASQTTELSMGSFGGFGLGSTPNPGAPKTNPFGGP---------------------FGNATTTTSN 1591

  Fly  1409 TTAAATPDA----PPAGLFASAAISNPSPFGS---PTTRAPASGGNIFGQAVKPSVFGQPAQAG- 1465
            ......|..    |.:..|.:...|.|:.|||   ..::.||..|           ||||:|.|
plant  1592 PFNMTVPSGELFKPASFNFQNPQPSQPAGFGSFSVTPSQTPAQSG-----------FGQPSQIGG 1645

  Fly  1466 --DSGGSI---------FGGGSASTPFGSSSIFGGGNT-QGAVGAPAAGSTSIFGQKVFGQSSAA 1518
              .:.||:         .|.|.....|||.:.|||.|. .|...|||:|..:..|....|..:|.
plant  1646 GQQALGSVLGSFGQSRQIGAGLPGATFGSPTGFGGSNPGSGLPNAPASGGFAAAGSSATGGFAAM 1710

  Fly  1519 APAAGG--NIFSNPVGSPQASPFGGGGNSIFGSPATAPPASGGSIFGG-GSSSGGFGSFTQTTPA 1580
            |.|..|  ...|.|.|...|...|.||.      |.|.|..||..||| ||.:||||.|     |
plant  1711 ASAGRGFAGASSTPTGGFAALASGSGGF------AGAAPGGGGGGFGGLGSGTGGFGGF-----A 1764

  Fly  1581 QGGFGGGFGQGGGGSVAQTGFGSPQAPQQQTTTPGGFGAKPVFGGSPAFGASPTFGGGATFGSPK 1645
            ..|..|||....||                    ||||.   |||.    |....|||
plant  1765 PQGSSGGFAGAAGG--------------------GGFGG---FGGQ----AQGQAGGG------- 1795

  Fly  1646 GFGGFGGASPVASPPPFGAAAKPAQ 1670
            ||..|||.|        ||..||::
plant  1796 GFSAFGGNS--------GATGKPSE 1812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup214	NP_652039.2	WD40	<31..>233	CDD:225201	41/228 (18%)
		WD40 repeat	38..86	CDD:293791	9/51 (18%)
		WD40 repeat	90..131	CDD:293791	9/40 (23%)
		WD40 repeat	139..173	CDD:293791	6/33 (18%)
LNO1	NP_001117499.2	WD40 repeat	100..144	CDD:293791	9/47 (19%)
		WD40 repeat	188..230	CDD:293791	8/45 (18%)
		Herpes_BLLF1	<1210..1651	CDD:282904	114/474 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000