Protein Alignment Nup214 and npp-10

DIOPT Version :9

• Sequence 1: NP_652039.2
• Gene: Nup214 / 46091
• FlyBaseID: FBgn0010660
• Length: 1711
• Species: Drosophila melanogaster
• Sequence 2: NP_001367842.1
• Gene: npp-10 / 175852
• WormBaseID: WBGene00003796
• Length: 1678
• Species: Caenorhabditis elegans
• Alignment Length: 675
• Identity: 170/675 - (25%)
• Similarity: 244/675 - (36%)
• Gaps: 247/675 - (36%)

  Fly  1071 ENKSFG---FGGFTGTGGTVGNTSSSPFSFGGLGSSLGFGGTAAAVPKSEPSSTATTSVATSAST 1132
            :|||||   |||.:...|..|..:.:..:.|..|               :|::.:.|:
 Worm     4 QNKSFGSSSFGGGSSGSGLFGQNNQNNQNKGLFG---------------QPANNSGTT------- 46

  Fly  1133 APFGIFSAALAKPSNSEPITTVTSNTTTITSKPTNVIASSSVTDAPSVTTTNAVTSSTDPIGGLF 1197
               |:|.||..||:.|  |....|||::|                                   |
 Worm    47 ---GLFGAAQNKPAGS--IFGAASNTSSI-----------------------------------F 71

  Fly  1198 SSVTICKPNTPADTTKPANIFGGGLSAGSFSFGGTIDASKGLFGSTKPVATAPTSV--TEANNK- 1259
            .|     |..|.:  ..:::||||.:          :|::.:||||...|.|.:|:  ..|||.
 Worm    72 GS-----PQQPQN--NQSSLFGGGQN----------NANRSIFGSTSSAAPASSSLFGNNANNTG 119

  Fly  1260 TDPI----STTPS-----AISTTTATTTVSSPAVVPAAVTAAVPATSSTTVTSSTAVPGSAFSFS 1315
            |..|    :..||     ..||.:.||....|           |.:|.|.:.:     |:..:.|
 Worm   120 TSSIFGSNNNAPSGGGLFGASTVSGTTVKFEP-----------PISSDTMMRN-----GTTQTIS 168

  Fly  1316 NAFSTLSA----GGAAAPTTSASAPLAAKSPTATSTGNNSSNSVFGGGFAVATSTAAPVASPFQS 1376
            .....:||    .|.:.........:|.:.  |..||..|:    |||...|::|.
 Worm   169 TKHMCISAMSKYDGKSIEELRVEDYIANRK--APGTGTTST----GGGLFGASNTT--------- 218

  Fly  1377 AAKSPVSSANIFGSI-PKAETSVFGGATTAPSNTTAAATPDAPPAGLFASAAISNPSPFGSPTTR 1440
               :...|:.:|||. .:.:||:||||:|:                          ||||..|:.
 Worm   219 ---NQAGSSGLFGSSNAQQKTSLFGGASTS--------------------------SPFGGNTST 254

  Fly  1441 APASGGNIFGQAVKPSVFGQPAQAGDSGGSIFGGGSASTPFGSSSIFGGGNTQGAVGAPAAGSTS 1505
            |                        ::|.|:||..:|:|...|.|:||.    ...|:...|||:
 Worm   255 A------------------------NTGSSLFGNNNANTSAASGSLFGA----KPAGSSLFGSTA 291

  Fly  1506 IFGQKVFGQSSAAAPAAGGNIFSNPVGSPQASPFGGGGNSIFGSPATAPPASGGSIFG--GGSSS 1568
            ..|...|||::      |.::|.|.  .||.:.    |.|:||:  |......||:||  |.:.:
 Worm   292 TTGASTFGQTT------GSSLFGNQ--QPQTNT----GGSLFGN--TQNQNQSGSLFGNTGTTGT 342

  Fly  1569 GGFGSFTQTTPAQGGFGGGFGQGGGGSVAQTGFGSPQAP--------QQQTTTPGG--FGAKP-- 1621
            |.||. .|..|.|...|..|   ||...|...||.|.|.        ...|...|.  |||||
 Worm   343 GLFGQ-AQQQPQQQSSGFSF---GGAPAATNAFGQPAAANTGGSLFGNTSTANTGSSLFGAKPAT 403

  Fly  1622 ----VFGGSP-----AFGASPTFGG---------GATFGSPKGFGGFGGASPVASPPPFGAAAKP 1668
                .||.:.     |||::.|.||         |..||:....|..||.        ||:..:.
 Worm   404 STGFTFGATQPTTTNAFGSTNTGGGLFGNNAAKPGGLFGNTTNTGTGGGL--------FGSQPQA 460

  Fly  1669 AQGNIF--ETLGGQESGLSFGNLAQ 1691
            :.|.:|  .|...|.....||||||
 Worm   461 SSGGLFGSNTQATQPLNTGFGNLAQ 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nup214	NP_652039.2	WD40	<31..>233	CDD:225201
		WD40 repeat	38..86	CDD:293791
		WD40 repeat	90..131	CDD:293791
		WD40 repeat	139..173	CDD:293791
npp-10	NP_001367842.1	Nucleoporin_FG	59..146	CDD:404514	31/140 (22%)
		Nucleoporin_FG	110..240	CDD:404514	36/163 (22%)
		Nucleoporin_FG	237..334	CDD:404514	42/164 (26%)
		Nucleoporin_FG	305..431	CDD:404514	44/137 (32%)
		Nucleoporin_FG	407..>487	CDD:404514	26/87 (30%)
		Nucleoporin2	777..919	CDD:397975
		Nup96	1259..1512	CDD:403363

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910